2027 Spring Co-op Upstream Automatic Control Development, Framingham, MA

About the Job

This co-op role provides hands-on exposure to upstream cell culture operations, process technologies, and digital and automation initiatives that support process development and lifecycle management. The successful candidate will work alongside scientists and engineers supporting the development and characterization of mammalian cell culture processes, implementation of new technologies, and investigation of process improvements for both development and commercial programs.

Main Responsibilities

• Develop and implement automated bioreactor control strategies by integrating mammalian cell culture operations, Process Analytical Technology (PAT), and cloud-based control software.
• Support MSAT development activities related to upstream bioreactor operation, including hands-on work in the lab and integration of PAT tools (e.g., Raman spectroscopy and online sensors) for real-time process monitoring.
• Develop and test control logic and software interfaces linking analytical equipment and bioreactor control systems to enable closed-loop and predictive feeding control.
• Assist with in-silico simulation, configuration, and testing of control strategies prior to and alongside lab implementation.
• Collaborate with scientists and engineers to ensure reliable data flow, system connectivity, and control performance across lab and digital platforms.
• Provide regular project updates and deliver a final technical presentation summarizing outcomes, learnings, and proposed next steps.

Basic Qualifications

• Currently pursuing a bachelor's, master's, or PhD degree in Chemical Engineering, Computational Science, Bioengineering, Biotechnology, Biochemistry or related fields with plans to graduate by Spring 2028
• Must be permanently authorized to work in the U.S. and not require sponsorship of an employment visa (e.g., H-1B or green card) at the time of application or in the future
• Must be enrolled in an accredited college or university throughout the duration of the co-op/internship
• Must be able to relocate to the office location and work 40hrs/week, Monday-Friday, for the full duration of the co-op/internship

Preferred Qualifications

• Hands-on experience with mammalian cell culture, aseptic technique, and basic cell biology techniques
• Experience with Python coding for data analysis, automation, or control-related applications
• Basic understanding of general concepts of cell biology, biochemistry, and laboratory procedures
• Ability to follow lab safety procedures
• Proficiency in Microsoft Office software (excel, PowerPoint, word)
• Excellent communication skills, written and verbal; able to effectively communicate with supervisor and team members
• Highly organized with a keen attention to details