Advisor – RNA Preclinical Pharmacology
Eli Lilly and Company
Summary
The successful candidate will have a strong research track record in RNA therapeutics, with excellent knowledge in all aspects of in vivo pharmacology. They will provide key technical knowledge and collaborate within a multidisciplinary team to support the development of next-generation RNA based therapeutics in various disease areas (including, but not limited to, cardiometabolic, cardiovascular, neuroscience and immunology).
Job description
Key Responsibilities
- Represent RNA therapeutics on cross functional project teams to drive projects through the development pipeline
- Active engagement on teams tasked with innovative challenges in the RNA therapeutics space
- Design, plan, and implement in vivo experiments to support the preclinical characterization of novel therapeutic molecules
- Expertise in tissue sample processing for gene expression, protein endpoints, or other complex biochemical endpoints (e.g RT-qPCR, JESS, ELISA, novel assay development)
- Assist in troubleshooting technical challenges for team members
- Adherence to rigorous scientific standards, data QC, and data analysis methods
- Provide written and verbal communication of work in lab reports and team meetings
- Accurate recording of all practical work: completion of electronic notebook to Lilly procedure quality standards
- General laboratory assistance, including ordering and receiving lab supplies, preparation of reagents, and maintain laboratory equipment
- General assistance with animal welfare and IACUC administrative work
- Ensure compliance with all health and safety regulations
- Passionate about contributing to a diverse and inclusive environment, every day
Basic Qualifications
- PhD in pharmacology, biology, biochemistry or related scientific field
- 1+ years of post-doctoral training or industry experience
Additional Skills/Preferences
- Direct experience working with RNA therapeutics in a drug development or applied therapeutics setting
- Experience in developing and working with in vivo models and assays to support drug discovery programs
- Hands-on competencies in designing and implementing in vivo pharmacological experiments including common dosing route and blood/tissue collection techniques
- Scientific background in cardiometabolic diseases
- Experience with animal welfare and IACUC work
- Knowledge and understanding of drug delivery and basic pharmacology concepts, is preferred
- Ability to adapt to changing platform needs, workflows and projects
- Execution-focused, independent, and team-oriented with an ability to thrive in a fast-paced and innovative environment
- Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data
- Embrace diversity of thought, background, and experience to deliver innovative solutions
Requirements
- PhD in pharmacology, biology, biochemistry or related scientific field
- 1+ years of post-doctoral training or industry experience
- Strong research track record in RNA therapeutics
- Excellent knowledge in all aspects of in vivo pharmacology
- Expertise in tissue sample processing for gene expression, protein endpoints, or other complex biochemical endpoints (e.g RT-qPCR, JESS, ELISA, novel assay development)
- Adherence to rigorous scientific standards, data QC, and data analysis methods
- Accurate recording of practical work in electronic notebook
- General laboratory assistance and equipment maintenance
- Animal welfare and IACUC administrative work
- Compliance with health and safety regulations
Benefits
- 401(k)
- Pension
- Vacation benefits
- Medical, Dental & Vision
- Prescription drug benefits
- Flexible spending accounts
- Life insurance
- Death benefits
- Employee assistance program
- Fitness benefits
- Employee clubs and activities
- Company bonus
Company overview
Eli Lilly and Company, commonly known as Lilly, is a leading American multinational pharmaceutical corporation headquartered in Indianapolis, Indiana. Founded in 1876 by Colonel Eli Lilly, the company has grown into one of the world's most valuable pharmaceutical enterprises, with operations in approximately 125 countries. Lilly specializes in developing and manufacturing innovative medicines across multiple therapeutic areas, including diabetes, oncology, neuroscience, immunology, and cardiometabolic diseases. The company is renowned for its groundbreaking work in insulin production, having been the first to mass-produce insulin and later developing the first commercially available insulin product in the U.S. Lilly's current portfolio includes blockbuster medications such as Mounjaro and Zepbound (tirzepatide) for diabetes and obesity, Trulicity (dulaglutide) for type 2 diabetes, Verzenio (abemaciclib) for breast cancer, and Taltz (ixekizumab) for autoimmune conditions. With approximately 47,000 employees worldwide, Lilly maintains a strong commitment to research and development, investing heavily in scientific innovation to address some of the world's most significant health challenges. The company operates with a mission to make life better for people around the world through the discovery and delivery of innovative medicines.