Summary

The Associate Director, Clinical Pharmacology drives the implementation, planning, and execution of clinical pharmacology activities across assigned projects, operating with a high degree of independence while partnering collaboratively within the function. In this role, the Associate Director leads trial-level activities and supports the development of compounds across relevant therapeutic areas, applying strong Pharmacokinetics/Pharmacodynamics (PK/PD) principles and model-based analyses to inform and advance drug development decisions. The Associate Director works cross-functionally to contribute to and help shape functional development strategies, while also serving as a mentor within the Clinical Pharmacology and Pharmacometrics organization to support the continued growth and development of the team.

Job description

Position Summary

The Associate Director, Clinical Pharmacology drives the implementation, planning, and execution of clinical pharmacology activities across assigned projects, operating with a high degree of independence while partnering collaboratively within the function. In this role, the Associate Director leads trial-level activities and supports the development of compounds across relevant therapeutic areas, applying strong Pharmacokinetics/Pharmacodynamics (PK/PD) principles and model-based analyses to inform and advance drug development decisions. The Associate Director works cross-functionally to contribute to and help shape functional development strategies, while also serving as a mentor within the Clinical Pharmacology and Pharmacometrics organization to support the continued growth and development of the team.

Key Responsibilities

Independently contribute to the development of compounds across various therapeutic areas with some supervision
Provide input to Phase 2/3 clinical study design and registrational strategy design for the compound with supervision
Accountable for Clinical Pharmacology and Pharmacometrics Plan
Lead design of Clinical Pharmacology Studies and manages data analysis, interpretation, and reporting
High proficiency in PK, PK/PD, and model informed drug development (MIDD) principles and analyses
Collaborate on cross-functional drug development teams, regulatory submissions, and departmental initiatives; serves as Clinical Pharmacology subject matter expert
Participate in interactions with health authorities; serves as Clinical Pharmacology subject matter expert
Lead or participate in departmental initiatives; may be involved in external initiatives based on proficiency
Provide expertise based on proficiency to Business Development teams

Qualifications & Experience

MS, PhD or PharmD in relevant field
5+ years' experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics knowledge, including experience with general drug development process and small molecule and/or biologic drug property characterization
In-depth knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics
Strong written and oral communication skills necessary to report on and deliver scientific presentations
Demonstrated ability to work in a dynamic team-oriented environment
Provide mentorship and guidance to staff and the CP&P function
Supervise a colleague in CP&P, as needed
Independently serve as the CP&P lead for one or more assets in the BMS drug development program
Programming experience is highly desired (e.g., NONMEM, R, and WinNonlin. SAS, Splus, etc.)
Quantitative data analysis, POP PK/PD, and data visualization skills are highly desired

Requirements

MS, PhD or PharmD in relevant field
5+ years' experience with demonstrated progression in Clinical Pharmacology and Pharmacometrics knowledge
Experience with general drug development process and small molecule and/or biologic drug property characterization
In-depth knowledge of current practices and issues in Clinical Pharmacology and Pharmacometrics
Strong written and oral communication skills necessary to report on and deliver scientific presentations
Demonstrated ability to work in a dynamic team-oriented environment
Provide mentorship and guidance to staff and the CP&P function
Supervise a colleague in CP&P, as needed
Independently serve as the CP&P lead for one or more assets in the BMS drug development program
Programming experience is highly desired (e.g., NONMEM, R, and WinNonlin. SAS, Splus, etc.)
Quantitative data analysis, POP PK/PD, and data visualization skills are highly desired

Benefits

Wellbeing Support
Retirement Benefits
Financial Protection Benefits
Medical, Dental & Vision
Life & Disability Insurance
Flexible Time Off
11 Paid Company Holidays
Paid Sick Leave
Paid Volunteer Days
Summer Hours Flexibility
Leaves of Absence
Global Shutdown

Company overview

Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.