Associate Director, Pharmacometrics (Pop PK and PK/PD)
Simulations Plus
Summary
The Associate Director, Pharmacometrics will lead cross-functional project teams through the successful completion of client goals. This role will engage in activities ranging from consultations on study design through the development and evaluation of models, the performance of simulations, and the presentation of results.
Job description
Job Responsibilities
- Independently develop and evaluate complex models and simulations
- Lead, manage, and collaborate effectively with cross-functional project teams to successfully support client requests
- Build partnerships with clients; provide strategic input and advice
- Serve as main point of contact for assigned clients and projects
- Consult with clients on study design through development and evaluation of models
- Provide valuable insight into the optimal use of modeling and simulation in drug development programs
- Clearly communicate and present modeling and simulation results to clients
- Use state-of-the-art software to develop, evaluate and apply PK, PK/PD and exposure-response models
- Formulate pharmacometric data analysis plans and data requirement documents, ensuring appropriateness of methods for data handling and analysis and compliance with current global regulatory guidance
- Perform model-based simulations to address critical development questions
- Write pharmacometric reports and regulatory documents
- Utilize internal resources to meet project timelines and budgets
- Share scientific knowledge and skills with other staff members
- Other duties as assigned
Qualifications
- Proficiency in Monolix, NONMEM, and R
- 6+ years of population PK and PK/PD professional modeling experience preferred
- Professional experience in application of Pharmacometrics to Clinical Pharmacology preferred
- Proficient at developing and delivering presentations
- Highly self-motivated and willing to take on challenges
- Possess excellent critical-thinking, problem-solving, and interpersonal skills
- Strong verbal and written communication
- Some travel required for meetings, trainings, and conferences
Education
- Master's degree in pharmacometrics, PK/PD, pharmaceutics, pharmacology, statistics, engineering, or related field
- PhD in pharmacometrics, PK/PD, pharmaceutics, pharmacology, statistics, engineering, or related field preferred
Requirements
- Proficiency in Monolix, NONMEM, and R
- 6+ years of population PK and PK/PD professional modeling experience preferred
- Professional experience in application of Pharmacometrics to Clinical Pharmacology preferred
- Proficient at developing and delivering presentations
- Highly self-motivated and willing to take on challenges
- Possess excellent critical-thinking, problem-solving, and interpersonal skills
- Strong verbal and written communication
- Some travel required for meetings, trainings, and conferences
- Master's degree in pharmacometrics, PK/PD, pharmaceutics, pharmacology, statistics, engineering, or related field
- PhD in pharmacometrics, PK/PD, pharmaceutics, pharmacology, statistics, engineering, or related field preferred
Benefits
- Fully remote work
- Flexible schedules
- Generous vacation policy
- Affordable health coverage
- Annual bonus
Company overview
Simulations Plus is a leading provider of modeling and simulation software for the pharmaceutical and biotechnology industries. Founded in 1996 and publicly traded on NASDAQ (SLP), the company specializes in developing advanced software solutions that accelerate drug discovery and development processes. Their flagship products include GastroPlus for oral absorption simulation, ADMET Predictor for property prediction, and DDDPlus for dissolution testing. These tools enable researchers to predict drug behavior, optimize formulations, and reduce the need for costly animal testing and clinical trials. Simulations Plus serves major pharmaceutical companies, biotech firms, and academic institutions worldwide, helping them make data-driven decisions throughout the drug development pipeline. The company's technology plays a crucial role in advancing precision medicine and improving the efficiency of bringing new therapies to market.