Associate Director Quantitative Pharmacology
Regeneron Pharmaceuticals
Summary
We are seeking a highly motivated Associate Director (AD) to join the Quantitative Pharmacology (QP) group. The Associate Director will lead model-informed drug development strategies supporting one or more therapeutic areas across modalities including antibodies, siRNA, and gene therapies. This role combines scientific depth with cross-functional leadership to inform dose selection, trial design, and regulatory strategy from early development through submission.
Job description
When & where:
- Work Location: Tarrytown, NY, Warren, NJ, Cambridge, MA or Remote, USA
- Work model/flexibility: 4 days per week onsite or remote
Discover your role:
- Driving model-informed development (MIDD) and pharmacometrics strategies in partnership with Clinical Pharmacology, Biostatistics, Clinical and Translational teams to support regulatory and clinical decision-making.
- Leading the Quantitative Pharmacology evaluation of one or more assets, accountable for timely delivery of population PK/PD, exposure–response, and translational modeling analyses.
- Representing Quantitative Pharmacology at program and governance meetings, communicating quantitative insights clearly to non-modeling audiences.
- Contributing to regulatory interactions and authoring key components of regulatory documents related to Quantitative Pharmacology (e.g., IB, briefing books, etc.).
- Mentoring and developing junior scientists and fostering a culture of scientific rigor and collaboration.
- Identifying and implementing process improvements, new modeling approaches, and innovative quantitative tools to enhance efficiency and impact.
- Ensuring analyses and documentation are of the highest scientific quality and regulatory compliance.
This may be the right role for you if you:
- Want to make a visible impact on the organization by driving data-driven decisions that shape clinical and regulatory strategy.
- Thrive in multi-disciplinary environments, bridging discovery, clinical, and commercial teams.
- Communicate complex modeling concepts clearly and persuasively to diverse stakeholders.
- Have strong collaboration and leadership skills, influencing cross-functional teams without formal authority.
- Can independently design, execute, and oversee multiple modeling workstreams simultaneously.
To be considered for this role, you must have:
- PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 7+ years of industry experience; or MS with 10+ years of relevant experience.
- Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
- Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
- Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
- Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.
Requirements
- PhD in Quantitative Pharmacology, Pharmacometrics, Engineering, or a related field with 7+ years of industry experience; or MS with 10+ years of relevant experience.
- Demonstrated expertise in population PK/PD, exposure–response, or mechanistic modeling (systems biology, or QSP) using tools such as NONMEM, Monolix, Simulx, MATLAB/Simbiology and R.
- Proven track record of delivering analyses supporting regulatory submissions and engaging directly with agencies (e.g., FDA, EMA, PMDA).
- Hands-on experience with a broad range of quantitative and computational tools and a strong publication record.
- Exceptional communication and interpersonal skills, with the ability to influence and partner effectively across technical and non-technical teams.
Benefits
- Annual bonuses
- Equity awards
- Pension or retirement benefits
- 401(k) company match
- Health and wellness programs
- Fitness centers
- Medical insurance
- Dental insurance
- Vision insurance
- Life and disability insurance
- Paid time off
- Family support benefits
Company overview
Regeneron Pharmaceuticals is a leading American biotechnology company founded in 1988 and headquartered in Tarrytown, New York. The company specializes in inventing, developing, and commercializing life-transforming medicines for people with serious diseases. Regeneron is renowned for its innovative antibody technologies and has developed several groundbreaking therapies, including EYLEA® for retinal diseases, DUPIXENT® for inflammatory conditions, and the COVID-19 antibody cocktail REGEN-COV®. The company operates with a strong focus on research and development across multiple therapeutic areas including ophthalmology, oncology, cardiovascular diseases, and rare genetic disorders. Regeneron's proprietary VelocImmune® technology platform enables the rapid generation of fully human monoclonal antibodies. With over 15,000 employees globally and annual revenues exceeding $14 billion, Regeneron has established itself as a major force in the biotechnology industry, consistently ranking among the top-performing pharmaceutical companies and maintaining a robust pipeline of investigational therapies.