Associate Director, Sourcing Strategy & Procurement
Madrigal Pharmaceuticals
Summary
The Associate Director, Strategic Sourcing will lead strategic sourcing initiatives and category management activities supporting Chemistry, Manufacturing & Controls (CMC), Supply Chain, and Quality Assurance (QA) functions. This role is responsible for developing and executing sourcing strategies, managing supplier relationships, negotiating contracts, driving value creation, mitigating supply risk, and ensuring alignment with business objectives in a dynamic and highly regulated biopharmaceutical environment.
Job description
Key Responsibilities
Strategic Sourcing & Category Management
- Develop and execute category strategies for CMC, Supply Chain, and Quality-related spend categories, including CDMOs, analytical and CMC activities, raw materials, APIs, excipients, packaging components, logistics, transportation and warehousing services, and quality and compliance consulting services.
- Conduct market assessments, supplier evaluations, and benchmarking to identify opportunities for cost savings, innovation, risk mitigation, and operational efficiency.
- Lead competitive sourcing events including RFIs, RFPs, RFQs, supplier selection, and contract negotiations.
Supplier Relationship Management
- Build and maintain strategic relationships with key suppliers and service providers.
- Establish supplier performance metrics and governance frameworks to monitor quality, delivery, service, innovation, and compliance.
- Facilitate regular business reviews with critical suppliers.
- Help define and track KPIs that measure sourcing and procurement performance, supplier reliability, regulatory/SOP adherence, and value creation across scientific and non-scientific categories.
- Collaborate with business stakeholders to resolve supplier performance issues and drive continuous improvement initiatives.
Contracting & Negotiations
- Lead complex commercial negotiations, including Master Service Agreements, Quality Agreements, Supply Agreements, Statements of Work, and pricing arrangements.
- Partner with Legal, Quality, Finance and business stakeholders to ensure contractual terms appropriately address risk, compliance, quality, intellectual property, and business requirements.
- Drive favorable commercial outcomes while maintaining strong supplier partnerships.
Cross-Functional Partnership
- Serve as a trusted advisor to CMC, Supply Chain, and Quality leadership teams.
- Support strategic initiatives including clinical and commercial product launches, technology transfers, manufacturing scale-up activities, and network optimization efforts.
- Collaborate with stakeholders to forecast sourcing needs and align procurement strategies with organizational priorities.
Risk Management & Compliance
- Identify and proactively mitigate supply chain, quality, operational, and financial risks associated with suppliers.
- Support business continuity planning and supplier risk assessments.
- Ensure sourcing activities comply with company policies, industry regulations, and GxP requirements.
Financial Management
- Develop sourcing business cases and total cost of ownership analyses.
- Deliver measurable value through cost savings, cost avoidance, working capital improvements, and supplier performance enhancements.
- Track and report sourcing metrics, savings, and category performance to leadership.
Qualifications
Education: Bachelor's degree in Supply Chain, Business, Engineering, Life Sciences, Chemistry, or related field required. MBA, MS, CPSM, CPM, or equivalent advanced degree/certification preferred.
Experience: 8+ years of strategic sourcing, procurement, supply chain, or category management experience. Minimum 5 years supporting pharmaceutical, biotechnology, or other highly regulated industries. Demonstrated experience leading enterprise-level sourcing strategies and complex supplier negotiations. Proven ability to design, lead, and execute large and complex RFP processes in highly cross-functional environments. Exceptional communication, stakeholder management, and leadership skills, with the ability to influence at all organizational levels.
Preferred Experience: Experience supporting CMC, Technical Operations, Manufacturing, Supply Chain, and/or Quality organizations. Knowledge of GxP regulations, pharmaceutical manufacturing, quality systems, and supply chain operations. Experience managing CDMOs and critical supply chain service providers.
Knowledge, Skills & Abilities: Strong strategic sourcing and category management expertise. Proven negotiation and contract management skills. Strong understanding of pharmaceutical supply chains and external manufacturing models. Ability to influence senior leaders and cross-functional stakeholders without direct authority. Excellent analytical, financial modeling, and problem-solving capabilities. Experience conducting supplier risk assessments and developing mitigation strategies. Strong project management and organizational skills. Excellent verbal, written, and presentation communication skills. Ability to thrive in a fast-paced, growth-oriented environment.
Leadership Competencies: Strategic thinker with strong business acumen. Collaborative and relationship-focused. Results-oriented with a continuous improvement mindset. Effective change agent capable of driving organizational adoption. Demonstrates integrity, accountability, and sound judgment. Balances commercial objectives with quality, compliance, and patient-focused priorities.
Travel: Approximately 15–25% travel, including supplier visits, manufacturing sites, and industry conferences as needed. Position will be based in Zug, Switzerland; Waltham, MA; or West Conshohocken, PA and will require 3 days per week in the office.
Requirements
- Bachelor's degree in Supply Chain, Business, Engineering, Life Sciences, Chemistry, or related field required
- 8+ years of strategic sourcing, procurement, supply chain, or category management experience
- Minimum 5 years supporting pharmaceutical, biotechnology, or other highly regulated industries
- Demonstrated experience leading enterprise-level sourcing strategies and complex supplier negotiations
- Proven ability to design, lead, and execute large and complex RFP processes in highly cross-functional environments
- Exceptional communication, stakeholder management, and leadership skills, with the ability to influence at all organizational levels
- Strong strategic sourcing and category management expertise
- Proven negotiation and contract management skills
- Strong understanding of pharmaceutical supply chains and external manufacturing models
- Ability to influence senior leaders and cross-functional stakeholders without direct authority
- Excellent analytical, financial modeling, and problem-solving capabilities
- Experience conducting supplier risk assessments and developing mitigation strategies
- Strong project management and organizational skills
- Excellent verbal, written, and presentation communication skills
- Ability to thrive in a fast-paced, growth-oriented environment
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Paid Time Off
- Flexible Work Arrangements
Company overview
Madrigal Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), a serious form of fatty liver disease. The company's lead product, Rezdiffra (resmetirom), is a once-daily, oral thyroid hormone receptor (THR)-β selective agonist that targets key underlying causes of MASH in the liver. Rezdiffra received FDA approval in 2024 as the first treatment for MASH with moderate to advanced liver fibrosis, representing a significant breakthrough in hepatology. Headquartered in Conshohocken, Pennsylvania, Madrigal is publicly traded on NASDAQ under the symbol MDGL. The company continues to advance its clinical development programs, including ongoing Phase 3 trials evaluating Rezdiffra for the treatment of compensated MASH cirrhosis. Madrigal's innovative approach addresses a critical unmet medical need in liver disease therapeutics.