Associate Scientist, Biology
Gilead Sciences
Summary
The Oncology department at Gilead Sciences is seeking an experienced and motivated Associate Scientist/Senior Associate Scientist with exceptional technical skills to support research programs focused on the discovery and development of novel therapies that mobilize the immune response against cancer.
Job description
The successful candidate will be instrumental in conducting experiments and help develop novel assays to test therapeutic hypotheses and advance immune engager therapeutic candidates to selectively target tumors.
Key Responsibilities
- Independently execute and analyze studies that support the pre-clinical characterization of immune engager candidates, with contributions to multiple projects
- Support target validation efforts through characterization and generation of cellular models
- Help develop novel, complex cell biology assays to model tumor biology
- Explore mechanism of action of immune engager molecules by functional and flow cytometry-based characterization of molecules
- Prepare and present findings to the team and at department-wide meetings
- Contribute figures to research reports, manuscripts, INDs, and patent filings
Basic Qualifications
- 4+ Years with BS
- 2+ Years with MS
Preferred Qualifications
- Industry research experience preferred (BS +4 years OR MS +2 years) in cancer immunology or related field with a record of achievements (publications)
- Great attention to detail with excellent organizational and record keeping skills
- Strong motivation, independence, and ability to think critically and act creatively to resolve problems
- Excellent communication and interpersonal skills and ability to integrate into a high-paced multidisciplinary environment
- Experience in running and developing cell-based assays (T cell-mediated killing assays, Jurkat reporter assays)
- Experience in conducting and optimizing cell-based assays, as well as performing studies to assess immune responses in human and animal models (including whole blood, PBMCs, and various primary cell subsets)
- Experience with gene knockdown (RNAi), knockout (CRISPR/Cas9), and overexpression techniques (transfection, viral transduction)
- Hands-on experience in general molecular biology methods, including basic flow cytometry, western blot, ELISA/Luminex/MSD
Requirements
- 4+ years of experience with a Bachelor's degree
- 2+ years of experience with a Master's degree
- Industry research experience in cancer immunology or related field
- Record of achievements (publications)
- Experience in running and developing cell-based assays (T cell-mediated killing assays, Jurkat reporter assays)
- Experience in conducting and optimizing cell-based assays
- Experience performing studies to assess immune responses in human and animal models (whole blood, PBMCs, primary cell subsets)
- Experience with gene knockdown (RNAi), knockout (CRISPR/Cas9), and overexpression techniques (transfection, viral transduction)
- Hands-on experience in general molecular biology methods, including basic flow cytometry, western blot, ELISA/Luminex/MSD
- Great attention to detail with excellent organizational and record keeping skills
- Strong motivation, independence, and ability to think critically and act creatively to resolve problems
- Excellent communication and interpersonal skills
- Ability to integrate into a high-paced multidisciplinary environment
Benefits
- Medical insurance
- Dental insurance
- Vision insurance
- Life insurance
- Paid time off
- Annual bonus
- Stock-based long-term incentives
Company overview
Gilead Sciences, Inc. is a leading American biopharmaceutical company headquartered in Foster City, California, that specializes in researching, developing, and commercializing innovative medicines for life-threatening diseases. Founded in 1987, Gilead has grown into a global healthcare leader with approximately 17,600 employees worldwide. The company's primary therapeutic focus areas include HIV/AIDS, viral hepatitis (hepatitis B and C), oncology, inflammation, and respiratory diseases. Gilead is renowned for its groundbreaking antiviral therapies, including Sovaldi and Harvoni for hepatitis C, and its comprehensive portfolio of HIV treatments such as Truvada, Atripla, and Biktarvy. The company also developed Veklury (remdesivir) for COVID-19 treatment. Gilead operates as a publicly traded company on the NASDAQ (GILD) and is a component of both the Nasdaq-100 and S&P 100 indices. Through strategic acquisitions like Kite Pharma and Immunomedics, Gilead has expanded into cell therapy and oncology, demonstrating its commitment to advancing medical science and improving patient outcomes globally.