Associate Scientist

Job Summary

The Kilo Lab Scientist plays a key role in translating laboratory-developed chemical processes into safe, robust, and executable manufacturing processes within the New Brunswick Kilo Lab and beyond. Working hands-on with multidisciplinary Chemical Process Development teams, the scientist is responsible for the preparation, scale-up, and execution of processes supporting the manufacture of GMP active drug substance for pharmaceutical development. The scientist leads and coordinates manufacturing campaign activities, including process design and scale-up, equipment selection and setup, materials planning, process safety evaluation review, recipe development, batch execution, equipment cleaning, process documentation, and post-campaign assessment. The role requires a combination of scientific understanding, practical problem-solving, and mechanical aptitude, with a strong commitment to safety, quality, and environmental compliance. Kilo Lab Scientists execute processes from laboratory scale through 200L and work directly with processing equipment throughout campaign preparation and manufacturing.

Responsibilities

• Lead the implementation and scale-up of chemical processes from the development laboratory into the New Brunswick Kilo Lab in support of clinical development and GMP active drug substance manufacturing.
• Work hands-on with chemists, engineers, analytical scientists, and other cross-functional partners to translate laboratory processes into safe, robust, and executable manufacturing operations.
• Plan, coordinate, and execute Kilo Lab manufacturing campaigns, including equipment selection and setup, raw material planning, process safety readiness, recipe preparation, batch execution, cleaning, and manufacturing documentation.
• Apply scientific and engineering principles to identify and resolve technical and operational challenges encountered during process scale-up and manufacturing.
• Review process safety information and translate identified process requirements and operating boundaries into appropriate manufacturing practices.
• Monitor and assess process performance during manufacturing and document observations, deviations, learnings, and opportunities for process improvement.
• Ensure manufacturing activities are conducted in accordance with applicable safety, GMP, environmental, and procedural requirements.
• Collaborate with development teams before and after campaigns to incorporate scale-up and manufacturing learnings into subsequent process development.
• Participate in the evaluation and implementation of new equipment, manufacturing technologies, and processing methodologies within the Kilo Lab.
• Contribute to a collaborative working environment through effective communication, knowledge sharing, and partnership across scientific and engineering disciplines.

Required Qualifications

• BS in Chemistry, Chemical Engineering, or a related scientific or engineering discipline with 1-3 years of experience.
• Demonstrated ability to apply scientific and technical principles to laboratory, process development, scale-up, or manufacturing activities.
• Strong problem-solving skills and the ability to manage multiple priorities in a dynamic laboratory and manufacturing environment.
• Ability and willingness to work hands-on with chemical processing equipment and perform activities associated with setup, operation, and execution of manufacturing processes.
• Strong interpersonal and communication skills with the ability to work effectively across scientific and engineering disciplines in a matrix environment.
• Ability to work independently, exercise sound technical judgment, and manage assigned activities with appropriate levels of supervision.
• Commitment to safe working practices, quality, and regulatory compliance.

Preferred Qualifications

• Advanced degree in Chemistry, Chemical Engineering, or a related scientific or engineering discipline.
• Relevant industry experience in laboratory process development, chemical process scale-up, pilot-scale operations, or pharmaceutical/chemical manufacturing.
• Familiarity with chemical processing equipment and unit operations used in synthetic chemical manufacturing.
• Knowledge of GMP manufacturing principles and process safety practices.
• Experience translating laboratory procedures into larger-scale manufacturing operations.
• Experience with emerging or intensified manufacturing technologies, including continuous or flow processing.
• Ability and interest in applying and expanding technical capabilities across process development and manufacturing, including supporting Development Engineering laboratory activities and Process Engineering activities associated with externally executed manufacturing campaigns.