Associate Scientist, In Vivo Pharmacology, Neuroscience
Bristol Myers Squibb
Summary
The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept.
Job description
Responsibilities
- Performs in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing
- Performs and/or supports stereotaxic surgery in mice
- Performs and analyzes pharmacodynamic (PD) and efficacy readouts, such as ddPCR/qPCR, Western blot, immunohistochemistry, or muscle physiology assays
Basic Qualifications
- Bachelor's Degree
- 2+ years of academic and / or industry experience
Preferred Qualifications
- Extensive mouse handling experience, including common dosing routes, and tissue collection from CNS and peripheral tissues required
- Proficiency in standard molecular biology or biochemical assays required
- Background in mouse genetics and/or neuroanatomy
- Experience with rodent stereotaxic surgery
- Familiarity with in vivo bioluminescence imaging
- Experience with mouse breeding or colony management
- Experience with immunohistochemistry techniques or muscle physiology assays
- Strong organizational and communication skills
- Ability to work independently and as part of a team
- Detail-oriented with a commitment to scientific rigor and reproducibility
- Adaptability in a fast-paced, collaborative research environment
Requirements
- Bachelor's Degree
- 2+ years of academic and / or industry experience
- Extensive mouse handling experience, including common dosing routes, and tissue collection from CNS and peripheral tissues
- Proficiency in standard molecular biology or biochemical assays
- Background in mouse genetics and/or neuroanatomy
- Experience with rodent stereotaxic surgery
- Familiarity with in vivo bioluminescence imaging
- Experience with mouse breeding or colony management
- Experience with immunohistochemistry techniques or muscle physiology assays
- Strong organizational and communication skills
- Ability to work independently and as part of a team
- Detail-oriented with a commitment to scientific rigor and reproducibility
- Adaptability in a fast-paced, collaborative research environment
Benefits
- Wellbeing Support
- Retirement Benefits
- Financial Protection Benefits
- Medical Insurance
- Dental Insurance
- Vision Insurance
- Life Insurance
- Disability Insurance
- Flexible Time Off
- Paid Company Holidays
- Paid Sick Leave
- Paid Volunteer Days
- Summer Hours Flexibility
- Leaves of Absence
- Global Shutdown
Company overview
Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.