Associate Scientist, Metabolic Biologist
Eli Lilly and Company
Summary
Cardiometabolic Research at Eli Lilly and Company advances preclinical research aimed at understanding and treating obesity and related metabolic diseases.
Job description
We are seeking a skilled, motivated, and versatile individual who can help to build a highly collaborative, successful drug discovery and development team in the Obesity research group in Boston. The successful candidate will use a strong in vivo pharmacology background and complementary wet laboratory experience to play a critical role in supporting end-to-end discovery efforts and established pipeline projects with an emphasis on anti-obesity therapeutics. The candidate will be responsible for setting up critical capabilities in the laboratory setting and working with other scientists within and across departments to achieve project and department goals.
Responsibilities
The Research Associate will perform and support in vivo pharmacology studies in rodent models, working under the direction of project scientists. In this role, you will implement study procedures with precision, collect and process biological samples, and document results accurately so that they can be analyzed and shared with the broader research team. The responsibilities include, but are not limited to, the following:
- Perform rodent handling, blood collection, and dosing by subcutaneous (SC), oral (PO), and intraperitoneal (IP) routes according to study protocols.
- Measure and record body weight, body composition, and food intake throughout the course of in vivo studies.
- Collect tissues at study termination and complete downstream sample processing for analysis.
- Perform molecular and biochemical assessments (qPCR, Western blot, ELISA, etc).
- Function independently, work within a team-oriented lab environment, and work within cross-functional project teams.
- Analyze data independently, keep accurate records, and report data in written and oral formats. Perform work in full compliance with Lilly Research Policies and complete all required training activities in the timeframe specified.
Requirements
- B.S. and/or M.S. in biology or a related scientific field
- 2+ years of laboratory experience including hands-on in vivo rodent research experience
- Demonstrated proficiency in rodent handling and dosing, tissue collection, and downstream sample processing
- Previous experience with metabolic disease models
- Prior work with jugular vein cannulation and continuous infusion models
- Familiarity with pharmacokinetic/pharmacodynamic (PK/PD) concepts
- Experience with tissue culture of adipose, liver, or muscle cells
Benefits
- 401(k)
- Pension
- Vacation benefits
- Medical insurance
- Dental insurance
- Vision insurance
- Prescription drug benefits
- Flexible spending accounts
- Life insurance
- Death benefits
- Well-being benefits
- Employee assistance program
- Fitness benefits
- Company bonus
Company overview
Eli Lilly and Company, commonly known as Lilly, is a leading American multinational pharmaceutical corporation headquartered in Indianapolis, Indiana. Founded in 1876 by Colonel Eli Lilly, the company has grown into one of the world's most valuable pharmaceutical enterprises, with operations in approximately 125 countries. Lilly specializes in developing and manufacturing innovative medicines across multiple therapeutic areas, including diabetes, oncology, neuroscience, immunology, and cardiometabolic diseases. The company is renowned for its groundbreaking work in insulin production, having been the first to mass-produce insulin and later developing the first commercially available insulin product in the U.S. Lilly's current portfolio includes blockbuster medications such as Mounjaro and Zepbound (tirzepatide) for diabetes and obesity, Trulicity (dulaglutide) for type 2 diabetes, Verzenio (abemaciclib) for breast cancer, and Taltz (ixekizumab) for autoimmune conditions. With approximately 47,000 employees worldwide, Lilly maintains a strong commitment to research and development, investing heavily in scientific innovation to address some of the world's most significant health challenges. The company operates with a mission to make life better for people around the world through the discovery and delivery of innovative medicines.