Associate Scientist, Pilot Plant
Bristol Myers Squibb
Summary
The Associate Scientist position will be part of the Pilot Plant and is responsible for scale-up and execution of upstream or downstream processes within Biologics Development's program portfolio. This role will work closely with Process Development and manufacturing teams within the BMS network to deliver robust, scalable, and economical processes for clinical and commercial supply. This position will report to the Manager of the Pilot Plant and will be based in Devens, MA.
Job description
Key Responsibilities
- Responsible for execution of non-GMP Pilot Scale Lab Operations in accordance with established work instructions and SOPs.
- Adherence to safety during execution and maintenance of a safe work environment.
- Operations may include (but not limited to) wave and bioreactor setup and execution, chromatography and filtration setup and execution, sample submission, media/buffer preparation, and run monitoring/troubleshooting.
- Prepare/review technical documents including campaign summary reports, batch records, and SOPs.
- Introduce, evaluate, and implement innovative new process technologies.
- Participate in cross-functional teams to support process investigations, process development, scale-up, and tech transfer to clinical and commercial manufacturing.
- Track performance of Scale-up data against bench-scale to aid Process Development teams in the development of scale-down models.
- Support digital and automation initiatives within the department.
Qualifications
- B.S. or M.S. in Chemical/Biochemical Engineering, Biotechnology, Biochemistry, or related biologics fields.
- Work experience requirements: 2-4 years of industry experience in Process Development, Pilot Operations, GMP manufacturing or related field.
- Strong knowledge of upstream process development and unit operations, including cell culture, mammalian bioreactors, and harvest; or downstream process development and unit operations, including chromatography, and filtration is preferred.
- Prior experience with single-use manufacturing and automation is a plus. Working knowledge of cGMP is a plus.
- Knowledge of automation, statistics, design of experiment, and data analysis is a plus.
- Excellent oral and written communication skills.
Requirements
- B.S. or M.S. in Chemical/Biochemical Engineering, Biotechnology, Biochemistry, or related biologics fields
- 2-4 years of industry experience in Process Development, Pilot Operations, GMP manufacturing or related field
- Strong knowledge of upstream process development and unit operations, including cell culture, mammalian bioreactors, and harvest; or downstream process development and unit operations, including chromatography, and filtration is preferred
- Prior experience with single-use manufacturing and automation is a plus
- Working knowledge of cGMP is a plus
- Knowledge of automation, statistics, design of experiment, and data analysis is a plus
- Excellent oral and written communication skills
Benefits
- Wellbeing Support
- Retirement Benefits
- Financial Protection Benefits
- Medical Insurance
- Dental Insurance
- Vision Insurance
- Life Insurance
- Disability Insurance
- Flexible Time Off
- Paid Company Holidays
- Paid Sick Leave
- Volunteer Days
- Summer Hours Flexibility
- Leaves of Absence
- Global Shutdown
Company overview
Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.