Associate Scientist - Process Sciences
Neurona Therapeutics
Summary
Neurona Therapeutics is an early stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for neurological diseases. Our ideal candidate is a self-motivated individual who has a passion for scientific research. This is a fantastic opportunity to join a small team, work on transformative science, and take part in building an exciting, science-driven company.
Job description
Responsibilities
- Contribute towards the development, optimization and scale-up of cell culture, harvest, fill, cryopreservation and thaw processes for interneuron manufacturing from pluripotent cells.
- Process optimization and characterization, scale-up and process transfer to clinical manufacturing site
- Provide manufacturing support. Participate in trouble shooting exercises and the diagnosis and resolution of production problems through data analysis and process/equipment characterizations.
- Participate and represent process sciences in project teams.
- Present data at team meetings. Generate scientific reports and contribute towards regulatory submissions.
- Will be required to participate in technology transfer and process monitoring activities.
- Some travel to CMO sites may be required.
- Must possess the ability to work independently or as a team.
- Maintain notebooks and electronic files associated with each experiment and contributes to the preparation of final experimental reports.
- Manage product and material inventories as needed throughout studies.
Required Qualifications
- Ph.D. in Biochemical Engineering, life sciences or related scientific field with 0-2 years of industrial experience.
- In depth experience in mammalian cell culture and/or culture and expansion of stem cells is a requirement.
- Experience in flow cytometry, immunocytochemistry, development of production processes using bioreactors is necessary.
- Excellent computer, organizational, written and verbal communication skills.
- Familiarity with cGMP requirements preferred.
- Must be able to work independently and in multi-disciplinary teams.
- Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance process productivity.
Requirements
- Ph.D. in Biochemical Engineering, life sciences or related scientific field with 0-2 years of industrial experience
- In depth experience in mammalian cell culture and/or culture and expansion of stem cells
- Experience in flow cytometry, immunocytochemistry, development of production processes using bioreactors
- Excellent computer, organizational, written and verbal communication skills
- Familiarity with cGMP requirements preferred
- Must be able to work independently and in multi-disciplinary teams
- Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance process productivity
Company overview
Neurona Therapeutics is a clinical-stage biotechnology company pioneering regenerative cell therapies for neurological disorders. The company specializes in developing allogeneic, off-the-shelf cell therapies derived from human pluripotent stem cells to treat chronic neurological conditions. Neurona's lead program focuses on NRTX-1001, an investigational cell therapy for drug-resistant focal epilepsy, which has shown promising results in early clinical trials. The company's proprietary platform enables the production of specific types of inhibitory interneurons that can restore neural circuit balance in the brain. Founded by leading neuroscientists, Neurona combines deep expertise in stem cell biology, neuroscience, and clinical development to address unmet medical needs in epilepsy, Alzheimer's disease, and other neurological disorders. The company's innovative approach represents a paradigm shift in treating chronic neurological conditions through regenerative medicine rather than symptom management alone.