Associate Scientist, Product Biochemistry
Regeneron Pharmaceuticals
Summary
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Associate Scientist to join our Product Biochemistry group, supporting in-depth characterization of therapeutic protein candidates for early-stage developability assessments. In this role, you will be part of a group that broadly participates in pre-clinical candidate developability assessments and technology innovation efforts designed to enhance our understanding of novel protein therapeutics using solution-state and computational approaches.
Job description
When & where
- Location: On-site in Tarrytown, NY
What you'll do
- Conduct sample preparation of protein therapeutics to support biochemical and biophysical characterization experiments, measuring heterogeneity, aggregation state, and thermal stability using liquid chromatography, light scattering, and other techniques to elucidate quality attributes of therapeutic candidates for developability assessment
- Perform early biochemical and biophysical assessment of novel protein therapeutics, providing input on experimental design and suggesting method optimization to address program needs or characterize attributes of novel protein therapeutics
- Analyze data and document experiments, results, and findings in an electronic laboratory notebook; draft protocols, and present work at group and departmental meetings
- Comply with lab safety standards and proactively contribute to a clean and safe lab environment
- Draft technical documents to support regulatory filings and contribute to drafting peer-reviewed publications, as needed
- Maintain instruments, contribute to drafting protocols, troubleshoot instrumental/experimental issues, and order/maintain supplies
Must-haves
- Bachelor's degree in Biochemistry, Chemical Engineering, Biophysics, or a related field
- Good laboratory practice skills such as preparing samples, buffers, documentation, and maintaining cleanliness
- Strong initiative and drive to complete tasks, with the ability and desire to learn new technologies
- Capable of working both independently and within a collaborative environment
- Excellent oral and written communication skills
- Experience with Microsoft Office suite (Excel, Word, and PowerPoint) for analysis and presentation of data
Preferred / nice-to-haves
- Experience with coding/scripting tools such as MATLAB
- Experience in automated chromatography (HPLC/UPLC/FPLC), differential scanning calorimetry/fluorimetry (DSC/DSF), spectroscopy (UV-Vis, fluorescence, FTIR, Raman, and/or circular dichroism), and/or static/dynamic light scattering (SLS/DLS/MALS) of protein and/or macromolecules
- Familiarity with Excel/MATLAB/JMP to facilitate analysis of complex analytical datasets
Requirements
- Bachelor's degree in Biochemistry, Chemical Engineering, Biophysics, or a related field
- Good laboratory practice skills such as preparing samples, buffers, documentation, and maintaining cleanliness
- Strong initiative and drive to complete tasks, with the ability and desire to learn new technologies
- Capable of working both independently and within a collaborative environment
- Excellent oral and written communication skills
- Experience with Microsoft Office suite (Excel, Word, and PowerPoint) for analysis and presentation of data
- Experience with coding/scripting tools such as MATLAB
- Experience in automated chromatography (HPLC/UPLC/FPLC), differential scanning calorimetry/fluorimetry (DSC/DSF), spectroscopy (UV-Vis, fluorescence, FTIR, Raman, and/or circular dichroism), and/or static/dynamic light scattering (SLS/DLS/MALS) of protein and/or macromolecules
- Familiarity with Excel/MATLAB/JMP to facilitate analysis of complex analytical datasets
Benefits
- Annual bonuses
- Incentive plans
- Equity awards
- Pension or retirement benefits
- 401(k) company match
- Health and wellness programs
- Fitness centers
- Insurance benefits
- Paid time off
- Family support benefits
Company overview
Regeneron Pharmaceuticals is a leading American biotechnology company founded in 1988 and headquartered in Tarrytown, New York. The company specializes in inventing, developing, and commercializing life-transforming medicines for people with serious diseases. Regeneron is renowned for its innovative antibody technologies and has developed several groundbreaking therapies, including EYLEA® for retinal diseases, DUPIXENT® for inflammatory conditions, and the COVID-19 antibody cocktail REGEN-COV®. The company operates with a strong focus on research and development across multiple therapeutic areas including ophthalmology, oncology, cardiovascular diseases, and rare genetic disorders. Regeneron's proprietary VelocImmune® technology platform enables the rapid generation of fully human monoclonal antibodies. With over 15,000 employees globally and annual revenues exceeding $14 billion, Regeneron has established itself as a major force in the biotechnology industry, consistently ranking among the top-performing pharmaceutical companies and maintaining a robust pipeline of investigational therapies.