Associate Scientist / Scientist I, Protein Sciences

Role Overview

We are seeking a detail-oriented, hands-on Associate Scientist or Scientist I in Protein Sciences to support our immunoprecipitation (IP) workflow. In this role, you will develop new IP protocols, validate antibodies by Western blot, prepare samples for downstream mass spectrometry (MS) and Western blot analysis, and keep IP operations running reliably as demand grows.

Key Responsibilities

• Develop new immunoprecipitation (IP) protocols and adapt existing ones for new targets, antibodies, and sample types, taking methods from initial design through robust, documented procedures.
• Execute established IP protocols with a high degree of reliability and reproducibility, delivering consistent results as request volume grows.
• Perform Western blot–based antibody validation to confirm specificity and performance before antibodies are introduced into the IP workflow.
• Prepare high-quality samples for downstream mass spectrometry (MS) and Western blot analysis.
• Troubleshoot assay issues and drive method optimization in collaboration with the team, documenting changes and their impact on results.
• Manage reagent and antibody inventories, tracking lot information and reordering supplies to prevent workflow disruptions.
• Maintain complete, accurate, and timely records of all experimental work using electronic lab notebooks (ELNs) and inventory management software, including protocols, sample tracking, and data entry.

Qualifications & Experience

• BS or MS in biochemistry, molecular biology, neuroscience, or a related field with 4–6 years of relevant industry or academic lab experience; or a PhD in a related field with 1–3 years of experience.
• Hands-on experience performing immunoprecipitation assays, with a strong working understanding of IP principles; experience developing or optimizing new IP protocols is strongly preferred. Experience working with neurons is a plus.
• Proficiency in Western blotting, including experience with antibody validation (e.g., specificity testing, titration, and lot-to-lot comparison).
• Experience using ELNs (e.g. Benchling) and inventory management software, with a demonstrated commitment to rigorous, timely documentation and sample tracking.
• Comfort working at the interface of biology and emerging technologies — experience or strong interest in integrating novel measurement modalities (e.g., quantum sensing, high-content imaging, multi-omics) into cell biology workflows is a plus.
• Experience collaborating with automation or software engineers to design experiments.
• A builder's mindset: comfortable operating in a fast-moving, early-stage environment where you'll help define processes, not just follow them.
• Strong organization and communication skills and the ability to lead scientifically while collaborating across disciplines spanning cross-functional teams.