Automation Engineer Associate II
BillionToOne
Summary
We are looking for an Automation Engineer Associate II to join our growing Process Engineering team responsible for innovative solutions to support the high-complexity and high-growth clinical laboratory. This is a dynamic, start-up environment that requires adaptability and the ability to quickly learn and apply new concepts. The Automation Engineer reports to the Automation Engineering Manager and is an onsite position.
Job description
Responsibilities
- End-to-end development, design, integration, and validation of automation systems and protocols on liquid handling platforms (Hamilton, Lynx, Agilent Bravo etc.) in the clinical laboratory
- Contribute to integration efforts between liquid handlers and LIMS, utilizing APIs/drivers to support bi-directional data transfer and sample tracking
- Identify, develop, and implement process improvements to design and improve robust laboratory procedures
- Collaborate with the clinical and R&D teams to transfer new products and procedures onto the automated platforms
- Provide training and guidance to employees in the operation, maintenance, and troubleshooting of new equipment
- Develop and prepare documentation for procedure changes, instrument validations, IQ/OQ/PQ, standard operating procedures, and related documents
Qualifications
- BS or higher in Engineering, Biology, Microbiology, Biophysics, Biochemistry, or related field
- 1 to 3 years of experience in assay automation on liquid handlers (i.e. Hamilton, Beckman, Agilent, Tecan, Dynamic Devices)
- Experience in a semi-automated laboratory environment
- Technical proficiency in laboratory automation and systems development
- Strong multi-tasking, project management, organizational, communication, and documentation skills
- Software development experience in one or more languages (Python preferred)
- Strong laboratory understanding with experience in next-generation sequencing library preparation
Nice-to-Haves
- Certification in one of the major liquid handling systems (Hamilton, Beckman, Agilent, Tecan)
- Experience working under regulatory environments such as CLIA, CAP, or FDA
- Experience with Clarity LIMS or other LIMS systems
- Experience with integrated systems
Requirements
- BS or higher in Engineering, Biology, Microbiology, Biophysics, Biochemistry, or related field
- 1 to 3 years of experience in assay automation on liquid handlers
- Experience in a semi-automated laboratory environment
- Technical proficiency in laboratory automation and systems development
- Strong multi-tasking, project management, organizational, communication, and documentation skills
- Software development experience in one or more languages (Python preferred)
- Strong laboratory understanding with experience in next-generation sequencing library preparation
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Family Bonding Leave
- Fertility Benefits
- Paid Time Off
- On-site Lunches
- Gym Access
- EV Charging
- Equity Options
- Corporate Bonus Program
Company overview
BillionToOne is a precision diagnostics company headquartered in Menlo Park, California, founded in 2016 with a mission to make molecular diagnostics more accurate, efficient, and accessible. The company has developed a proprietary Quantitative Counting Templates (QCT) molecular counting platform that can accurately count DNA molecules at the single-molecule level, enabling unprecedented sensitivity in disease detection. BillionToOne operates as a publicly traded company on NASDAQ under the symbol BLLN, having completed a successful IPO in 2025. The company's diagnostic platforms include UNITY Complete for non-invasive prenatal testing, which assesses fetal risk for recessive conditions and aneuploidies from a single maternal blood sample, and Northstar oncology products for cancer therapy selection and treatment response monitoring. With over 500 employees and multiple CLIA/CAP accredited laboratories, BillionToOne represents a significant advancement in quantitative molecular diagnostics, combining breakthrough science with scalable commercial operations to transform healthcare delivery.