Bioinformatics Scientist I
Foundation Medicine
Summary
The Scientist I, Bioinformatics develops novel methods for detecting, reporting and analyzing alterations in tumor DNA and RNA, while optimizing existing methods. The incumbent provides scientific and technical contributions for a designated project on an interdisciplinary team. The Scientist I, Bioinformatics is also responsible for supporting novel biomarker and companion diagnostics development by mining and analyzing various types of data generated during the product development and validation process.
Job description
Key Responsibilities
- Partner within an interdisciplinary team of Biochemists, Bioinformatics Scientists, Computational Biologists, Data Scientists, focused on developing diagnostic products using massively parallel sequencing of tumor genomic DNA and RNA.
- Contribute to the development of new methods and algorithms to identify and characterize alterations in tumor DNA and RNA derived from clinical cancer specimens.
- Enhance existing methods, improving their assay capabilities as well as their technical robustness.
- Process, analyze, and interpret high volumes of data for the development and validation of methods.
- Monitor and evaluate analytical aspects of new and emerging technologies.
- Present scientific and technical data to colleagues in a clear and cohesive manner.
- Prepare project timetables, schedules and deliverables.
- Provide independent contributions.
Basic Qualifications
- Master’s Degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline
- 1+ years of industry or academic medical center professional experience or post-doctorate work
- Proficiency with programming and scripting languages R and Python
Preferred Qualifications
- PhD degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline
- 3+ years of industry experience
- Strong scientific understanding of molecular biology and genomics
- Facility with additional programming and scripting languages
- Experience contributing to a complex production analytical system
- Experience developing algorithms for analysis of biological data
- Prior experience with high-throughput sequencing
- Experience in cancer research, including a working understanding of computational approaches for cancer genome analysis
- Excellent teamwork, time management and organizational skills
- Ability to work independently in a multidisciplinary, fast-paced, dynamic, and results-oriented environment
- Ability to present data to a multidisciplinary audience in a clear and cohesive manner
- Understanding of HIPAA and importance of privacy of patient data
- Strong interpersonal skills that include collaboration and creative problem solving
- Impeccable documentation practices and attention to detail
- The ability to prioritize and complete tasks in a timely manner
Requirements
- Master’s Degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline
- 1+ years of industry or academic medical center professional experience or post-doctorate work
- Proficiency with programming and scripting languages R and Python
- PhD degree in Biochemistry, Bioinformatics, Computational Biology, Computer Science or similar discipline
- 3+ years of industry experience
- Strong scientific understanding of molecular biology and genomics
- Facility with additional programming and scripting languages
- Experience contributing to a complex production analytical system
- Experience developing algorithms for analysis of biological data
- Prior experience with high-throughput sequencing
- Experience in cancer research, including a working understanding of computational approaches for cancer genome analysis
- Excellent teamwork, time management and organizational skills
- Ability to work independently in a multidisciplinary, fast-paced, dynamic, and results-oriented environment
- Ability to present data to a multidisciplinary audience in a clear and cohesive manner
- Understanding of HIPAA and importance of privacy of patient data
- Strong interpersonal skills that include collaboration and creative problem solving
- Impeccable documentation practices and attention to detail
- The ability to prioritize and complete tasks in a timely manner
Benefits
- Discretionary annual bonus
- Company benefits
Company overview
Foundation Medicine is a leading precision medicine company headquartered in Boston, Massachusetts, that specializes in developing and commercializing comprehensive genomic profiling assays for cancer diagnosis and treatment. Founded in 2010 as a spin-off from the Broad Institute, the company leverages next-generation sequencing technology to provide molecular information that helps guide personalized cancer therapy decisions. As a subsidiary of Roche since 2018, Foundation Medicine offers a portfolio of diagnostic tests including FoundationOne CDx, FoundationOne Liquid, and FoundationOne Heme, which analyze solid tumors, hematologic malignancies, and sarcomas. The company's mission is to transform cancer care by delivering high-quality biomarker testing throughout a patient's journey, from initial diagnosis to ongoing management. With over 1,000 employees and operations in Boston, North Carolina, and Germany, Foundation Medicine collaborates extensively with biopharmaceutical partners to accelerate drug development and advance cancer research through its extensive genomic database containing profiles from more than 300,000 patients.