Bioinformatics Scientist II
CareDx, Inc.
Summary
CareDx is a leading precision medicine diagnostics company advancing care in transplant, specialty oncology, and cell therapy. We are seeking a motivated and innovative Bioinformatics Scientist I/Scientist II to join our dynamic R&D team. In this role, you will contribute to the advancement of innovative research, applying your expertise to experiment design, data analysis, algorithm development, and validation studies in support of diagnostic projects.
Job description
Responsibilities
- Independently initiate, design, and analyze digital PCR and/or NGS experiments to develop and/or improve high-value diagnostic tests.
- Develop, optimize, and maintain analysis pipelines to support overall diagnostic product development and commercial launch.
- Perform basic analysis of high-dimensional data and collaborate with wet lab scientists, the clinical operations team, and other cross-functional teams for comprehensive data interpretation and troubleshooting and make scientifically supported recommendations.
- Provide expert support and guidance regarding experiment design and data analysis for assay development, publication, and decision-making to the broader scientific team.
- Collaborate across multiple departments to ensure seamless integration of scientific insights into broader research goals.
- Participate in software code review, documentation, testing, and version control.
- Work within applicable quality systems such as CLIA/CAP and other regulated software development processes.
- Communicate complex computational findings to scientists who may not have a bioinformatics background.
- Provide and update commercial-use software tools for LDT diagnostic tests.
Minimum Education, Experience, & Specialized Knowledge (Required)
- MS in bioinformatics, molecular biology, chemistry, or a related field with 1-2 years of relevant experience (Scientist I) or 3+ years (Scientist II).
- Candidates with a BS and significant experience (5+ years) may also be considered.
- Solid foundation in bioinformatics analysis and Python scripting.
- Strong interdisciplinary communication skills to foster collaboration and effective knowledge exchange.
- Excellent organizational skills with acute attention to detail, ensuring high-quality outputs in a fast-paced environment.
Preferred Qualifications
- Industry experience developing diagnostic assays is preferred.
- Previous experience in liquid biopsy, working with clinical samples, clinical operations, algorithm and QC development and validation is strongly preferred.
Requirements
- MS in bioinformatics, molecular biology, chemistry, or a related field with 3+ years of relevant experience (Scientist II)
- BS with 5+ years of significant experience may also be considered
- Solid foundation in bioinformatics analysis
- Proficiency in Python scripting
- Strong interdisciplinary communication skills
- Excellent organizational skills with acute attention to detail
- Industry experience developing diagnostic assays (preferred)
- Experience in liquid biopsy, clinical samples, clinical operations, algorithm and QC development and validation (strongly preferred)
Benefits
- Competitive base salary
- Incentive compensation
- Health and welfare benefits
- Gym reimbursement program
- 401(k) savings plan match
- Employee Stock Purchase Plan
- Pre-tax commuter benefits
- Living Donor Employee Recovery Policy
Company overview
CareDx, Inc. is a leading precision medicine company specializing in transplant diagnostics and patient care solutions. Founded 25 years ago, the company focuses on the discovery, development, and commercialization of clinically differentiated, high-value diagnostic solutions for transplant patients and caregivers. Headquartered in Brisbane, California, with operations across the United States, Europe, and Australia, CareDx offers a comprehensive portfolio of non-invasive surveillance tests including AlloMap® Heart (gene expression testing), AlloSure® Kidney, Heart, and Lung (donor-derived cell-free DNA solutions), and HeartCare® (multimodality testing). The company also provides lab products for HLA typing, digital transplant solutions for patient management, and specialized transplant pharmacy services. With approximately 651 employees as of 2024, CareDx has established itself as the leading provider of genomics-based information for transplant patients, generating $333.8 million in revenue in 2024. The company's innovative approach combines advanced genomics, bioinformatics, and clinical evidence to transform transplant patient care throughout the entire transplant journey.