Clinical Bioinformatics Analyst I
Foundation Medicine
Summary
The Analyst I, Clinical Bioinformatics is responsible for analysis and delivery of next generation sequence data in a high-complexity clinical diagnostic laboratory to clinicians, pharmaceutical partners, and academic collaborators. In addition, the position is responsible for collecting and presenting quality metrics and reviewing variant reports.
Job description
About the Job
The Analyst I, Clinical Bioinformatics is responsible for analysis and delivery of next generation sequence data in a high-complexity clinical diagnostic laboratory to clinicians, pharmaceutical partners, and academic collaborators. In addition, the position is responsible for collecting and presenting quality metrics and reviewing variant reports.
This is a regulated position and additional information may be available from QA on the qualifications for this role pertaining to regulatory guidelines.
Key Responsibilities
- Develop annotated genomic profiles of somatic aberrations based on massively-parallel sequencing (Next Generation Sequencing or NGS) data in cancer-patient samples study.
- Review genomic variant calls using proprietary and publicly available tools, including but not limited to the Integrative Genomics Viewer (IGV), in close collaboration with the scientific team.
- Provide test results according to Standard Operating Procedures (SOPs) with the best possible quality within defined turn-around times.
- Collaborate with technical teams in specifying requirements for tools to enhance workflow efficiency and robustness.
- Other duties as assigned.
- Comply with FMI's attendance policies
Basic Qualifications
- Bachelor's Degree
- Prior experience working with bioinformatics tools and databases
Preferred Qualifications
- Master's Degree in Bioinformatics, Biology, or a life science
- Substantive genomics research experience in rigorous academic setting
- Experience with bioinformatics tools and databases, including the National Center for Biotechnology Information (NCBI), University of California Santa Cruz (UCSC) Genome Browser, and Integrative Genomics Viewer (IGV)
- Scripting ability in Python or Perl
- Facility with UNIX environment
- Experience with Next-Generation Sequencing
- Experience working within a CLIA-certified clinical diagnostics laboratory
- Ability to work in a lab environment in the presence of chemicals and regents
- Ability to work weekend or off-hours shift work
- Strong interpersonal skills that include excellent skills in written and oral communication, collaboration, and problem solving
- Demonstrated history of successfully managing multiple concurrent initiatives and maintaining one's own workflow
- Demonstrated ability to meet project deadlines
- Ability to work well under pressure while maintaining a professional demeanor
- Understanding of HIPAA and the importance of patient data privacy
- Commitment to reflect FMI's values: Integrity, Courage, and Passion
Requirements
- Bachelor's Degree
- Prior experience working with bioinformatics tools and databases
- Master's Degree in Bioinformatics, Biology, or a life science (preferred)
- Substantive genomics research experience in rigorous academic setting (preferred)
- Experience with bioinformatics tools and databases, including NCBI, UCSC Genome Browser, and IGV (preferred)
- Scripting ability in Python or Perl (preferred)
- Facility with UNIX environment (preferred)
- Experience with Next-Generation Sequencing (preferred)
- Experience working within a CLIA-certified clinical diagnostics laboratory (preferred)
- Ability to work in a lab environment in the presence of chemicals and reagents (preferred)
- Ability to work weekend or off-hours shift work (preferred)
- Strong interpersonal skills including written and oral communication, collaboration, and problem solving (preferred)
- Demonstrated history of managing multiple concurrent initiatives and maintaining own workflow (preferred)
- Demonstrated ability to meet project deadlines (preferred)
- Ability to work well under pressure while maintaining a professional demeanor (preferred)
- Understanding of HIPAA and patient data privacy (preferred)
Benefits
- Discretionary annual bonus
- Company benefits
Company overview
Foundation Medicine is a leading precision medicine company headquartered in Boston, Massachusetts, that specializes in developing and commercializing comprehensive genomic profiling assays for cancer diagnosis and treatment. Founded in 2010 as a spin-off from the Broad Institute, the company leverages next-generation sequencing technology to provide molecular information that helps guide personalized cancer therapy decisions. As a subsidiary of Roche since 2018, Foundation Medicine offers a portfolio of diagnostic tests including FoundationOne CDx, FoundationOne Liquid, and FoundationOne Heme, which analyze solid tumors, hematologic malignancies, and sarcomas. The company's mission is to transform cancer care by delivering high-quality biomarker testing throughout a patient's journey, from initial diagnosis to ongoing management. With over 1,000 employees and operations in Boston, North Carolina, and Germany, Foundation Medicine collaborates extensively with biopharmaceutical partners to accelerate drug development and advance cancer research through its extensive genomic database containing profiles from more than 300,000 patients.