Clinical Program Manager
Revolution Medicines
Summary
This is a unique opportunity for a Clinical Operations Professional. As a Clinical Program Manager (CPM), you will be responsible for acting as a central contact for the Clinical Study Team(s) and assist with the execution and management of Revolution Medicines (RevMed) clinical trials.
Job description
- Adhere to Clinical Standard Operating Procedures (SOP), Good Clinical Practice (GCP) and International Conference on Harmonization (ICH) Guidelines.
- Be a team leader, providing guidance and oversight for the successful management of all aspects of clinical trials within timelines and designated program budgets.
- Partner with cross-functional teams to manage, adjust, and revise project timelines and budgets as needed.
- Analyze data health metrics to be shared with stakeholders.
- Actively partner with cross-functional teams and vendors to drive the query resolution and data listings review process to meet objectives in a timely and efficient process.
- Conduct risk management, contingency, and scenario planning.
- Supervise, communicate project status/issues, and problem solve to ensure project team goals are met.
- Participate in the development of all study-related documentation, including study protocols.
- Actively contributes in the selection and management of contract research organizations (CROs) and/or vendors, including development of requests for proposals (RFPs).
- Use all available tools to track, oversee, and communicate on program status to all key stakeholders.
- Participate in other Clinical Operations activities as appropriate.
- Leads a larger, more complex trial with some oversight from senior members of Clinical Operations.
- With minimal support, lead cross-functional Clinical Study Execution Team (CSETs).
- Participate in and contribute to SOP development, implementation, and training.
- Support junior team members through mentorship.
Requirements
- RN or Bachelor's or Masters degree in biological sciences or health-related field required
- 8+ years direct Clinical Operations experience in the pharmaceutical or biotech industry
- Minimum of 4 years of cross-functional study management or related leadership experience in life sciences
- Strong working knowledge of FDA Regulations, ICH Guidelines, and GCP
- Proven ability to successfully start-up, manage, and close-out clinical trials
- Experience in selection of CROs/vendors and management of external resources
- Excellent written/verbal communication and interpersonal skills
- Proficiency in Microsoft Office Suite (Outlook, MS Word, Excel, PowerPoint)
- Travel may be required (~25%)
Benefits
- Competitive cash compensation
- Equity awards
- Health benefits
- Learning and development opportunities
Company overview
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies for RAS-addicted cancers. The company is pioneering a new class of therapeutics that target oncogenic RAS mutations, which are among the most common drivers of human cancers. Revolution Medicines employs a unique approach to drug discovery, leveraging deep insights into RAS biology to develop small molecule inhibitors that can address previously undruggable targets. Their pipeline includes multiple clinical-stage candidates designed to inhibit various RAS pathway mutations, with a particular focus on KRAS G12C and other RAS variants. The company's scientific platform combines structural biology, medicinal chemistry, and computational approaches to design highly selective inhibitors. Revolution Medicines aims to transform cancer treatment by developing therapies that can overcome resistance mechanisms and provide durable clinical benefits for patients with RAS-driven malignancies. Their research represents a significant advancement in the field of targeted cancer therapy, addressing one of the most challenging areas in oncology drug development.