Director, Real-World Evidence & Health Outcomes, mRNA Vaccines

Position Summary

The Director, Real-World Evidence & Health Outcomes (RWE-HO), mRNA Vaccines will provide scientific and strategic leadership for the development and delivery of real-world evidence supporting GSK's mRNA vaccine portfolio, with a primary focus on influenza. The role will shape evidence generation across late-stage development, launch and post-marketing phases, with particular responsibility for post-marketing vaccine effectiveness studies in the United States.

Responsibilities

• Lead and contribute to the integrated RWE-HO strategy for mRNA influenza vaccines, aligned with clinical development, medical, regulatory and commercialization priorities.
• Translate strategic evidence gaps into clear research questions and fit-for-purpose study designs across pre-launch, launch and post-marketing phases.
• Provide expert scientific input to governance decisions, investment choices, evidence prioritization and risk mitigation.
• Lead the design, implementation and interpretation of post-marketing influenza vaccine effectiveness studies in the United States and other geographies.
• Ensure studies meet appropriate standards of scientific rigor, transparency, reproducibility and fitness for their intended decision-making purpose.
• Build productive collaborations with US academic investigators, healthcare systems, data partners and vaccine effectiveness research networks.
• Partner effectively with Clinical Development, Epidemiology, Medical Affairs, Regulatory, Safety, Biostatistics, Market Access, Data Science and Commercial teams.
• Lead multiple complex projects, budgets and external research collaborations, ensuring quality, timely delivery and appropriate escalation of risks.
• Influence senior stakeholders without direct authority and communicate complex epidemiological concepts in a clear, decision-focused manner.
• Mentor colleagues and contribute to strengthening RWE-HO capabilities, standards and innovation across the organization.

Basic Qualifications

• PhD, ScD, DrPH, MD, PharmD, MPH or equivalent advanced degree in epidemiology, public health, pharmacoepidemiology, health outcomes research or a related quantitative discipline.
• 5+ years experience in real-world evidence, epidemiology or health outcomes research within the pharmaceutical or vaccine industry, academia, public health or a comparable environment.
• Experience designing, conducting and interpreting post-marketing vaccine studies in the United States.
• Research experience with vaccine effectiveness studies.
• Experience using large US healthcare databases, including administrative claims, electronic health records or linked real-world datasets.
• Experience leading complex studies from concept through delivery, interpretation and scientific dissemination.
• Demonstrated effectiveness in global, cross-functional matrix teams and in managing internal and external stakeholders.

Preferred Qualifications

• Direct experience with influenza vaccine effectiveness studies in the United States.
• Experience with US Medicare, commercial claims, EHR and linked claims/EHR data.
• Knowledge of US influenza vaccination recommendations, vaccine delivery and healthcare systems.
• Experience studying severe influenza, hospitalization, cardiovascular complications or other downstream outcomes.
• Experience leading global evidence-generation plans or multi-country observational studies.