Director, Translational Medicine, Neurology
Bristol Myers Squibb
Summary
The Director of Translational Medicine (TM) will be a translational team lead for neurological and neuropsychiatric indications and be responsible for setting strategy for translational activities including clinical biomarker activities to support drug development programs. This individual will assume translational lead responsibilities for assets such as serving as a TM representative on global program teams, biomarker representative on study teams, setting up biomarker plans for individual trials and ensuring appropriate collection and timely analysis and reporting of final biomarker data. The individual will also be responsible for answering key TM questions related to the assigned assets and diseases via collaboration with TM laboratory team and/or academic thought leaders.
Job description
Key Responsibilities
- Designs and implements program-specific late development biomarker/translational plans, responsible for aiding in creation of clinical protocols, SAPs, SOWs, lab manual, and interfacing with CRO for execution of services, in conjunction with Biospecimen Operations and Procurement.
- Determines appropriate assays and vendors for clinical biomarkers, and manages outsourcing of biomarker assay development and validation partnering with Translational Sciences colleagues when applicable.
- Manages clinical biomarker data delivery and analysis and associated timelines by working with relevant internal functions and CROs.
- Prepares and delivers internal and external translational/biomarker presentations.
- Maintains timelines for biomarker data related publication through interaction with Medical Communications and Publication team as needed.
- Keeps up-to-date on relevant scientific/technical literature in order to apply external knowledge to internal research programs as appropriate and acts as a subject-matter expert within the team to critically evaluate the literature regarding the asset and disease biology.
- Works with TM laboratory scientists and academic TLs to address nonclinical translational questions.
- Participates in post-hoc biomarker analysis and publication efforts.
- Supports regulatory submissions and regulatory interactions as needed.
Qualifications & Experience
- PhD or MD/PhD in neuroscience with 10+ years of translational medicine experience.
- 7+ years of late stage clinical biomarker experience in biotech/pharma.
- Recognized expertise in translational biomarkers in neurology space.
- Experience in late-stage drug development and activities required for and related to clinical trial initiation, maintenance and completion.
- Strong verbal and written communication skills.
- Experience in interacting with CROs and TLs to manage projects and timelines.
- Proven scientific/leadership expertise (working in teams, mentoring people, managing projects).
- Accountable for timelines and deliverables.
- Prioritizes risks and implements contingency plans.
- Communicates regularly; prepares and delivers presentations within the department, to governance and senior leadership bodies, and externally as requested.
- Recognizes cross-functional issues and communicates within the larger organization.
- Provides expert guidance to multi-disciplinary teams and senior management.
- Has a track record of delivering results, driving continuous improvements, and building effective cross-functional networks.
Requirements
- PhD or MD/PhD in neuroscience
- 10+ years of translational medicine experience
- 7+ years of late stage clinical biomarker experience in biotech/pharma
- Recognized expertise in translational biomarkers in neurology space
- Experience in late-stage drug development and clinical trial initiation, maintenance and completion
- Strong verbal and written communication skills
- Experience interacting with CROs and TLs to manage projects and timelines
- Proven scientific/leadership expertise (working in teams, mentoring people, managing projects)
- Accountable for timelines and deliverables
- Prioritizes risks and implements contingency plans
- Communicates regularly and delivers presentations to governance and senior leadership
- Recognizes cross-functional issues and communicates within the larger organization
- Provides expert guidance to multi-disciplinary teams and senior management
- Track record of delivering results, driving continuous improvements, and building effective cross-functional networks
Benefits
- Wellbeing Support
- Retirement Benefits
- Financial Protection Benefits
- Medical, Dental & Vision
- Life & Disability Insurance
- Flexible Time Off
- 11 Paid Company Holidays
- Paid Sick Leave
- Paid Volunteer Days
- Summer Hours Flexibility
- Leaves of Absence
- Annual Global Shutdown
Company overview
Bristol Myers Squibb is a global biopharmaceutical company dedicated to discovering, developing, and delivering innovative medicines that help patients prevail over serious diseases. Founded in 1887 and headquartered in Princeton, New Jersey, the company operates with a unique BioPharma strategy that combines the reach and resources of a major pharmaceutical company with the entrepreneurial spirit and agility of a biotech firm. BMS focuses on transformative therapies in key therapeutic areas including oncology, hematology, immunology, cardiovascular disease, and fibrosis. The company has built a sustainable pipeline of potential therapies and leverages translational medicine and data analytics to deliver the right medicine to the right patient at the right time. With over 10,000 employees worldwide, Bristol Myers Squibb maintains a strong commitment to scientific excellence, patient-centric innovation, and global health equity through its foundation. The company's portfolio includes groundbreaking treatments such as Opdivo (nivolumab) for cancer, Eliquis (apixaban) for cardiovascular conditions, and Orencia (abatacept) for autoimmune diseases, among others.