Engineer I, Process Development, Pilot Scale Operations
Moderna
Summary
The Pilot Scale Operations team is seeking a highly skilled and motivated full-time individual to support Nucleic Acid pilot-scale production. Qualified candidates will have relevant academic or industry experience in solution preparation, RNA processing, sterile fill/finish and/or tangential flow filtration experience, and an understanding of scaling and technology transfer of these unit operations. A successful candidate should have exposure to large and small-scale equipment maintenance and troubleshooting; as well as authoring and updating equipment specific SOPs. This position will require excellent communication and organizational skills, as well as a focus on operational excellence and process optimization. A successful candidate must demonstrate the independent drive and collaborative spirit to operate in a dynamic, fast-paced environment.
Job description
Here's What You'll Do
- Be the receiving unit for technology transfer from Moderna's Process Development teams, focusing on nucleic acid development, enzyme reactions, and scale-up
- Assist other development scientists / engineers in defining process development and scale-up strategy, and implementing process control strategies
- Operate, maintain, and troubleshoot custom equipment used to manufacture Formulations batches
- Characterize product attributes through collaboration with analytical and technical teams
- Demonstrate and implement lab best practices
- Update and write standard operating procedure (SOPs) associated with production as needed
- Practice safe work habits and adhere to Moderna safety procedures and guidelines
- Adhere to documented waste handling procedures to respect environmental regulations
Here's What You'll Need (Basic Qualifications)
- Demonstrated success in bioprocess development, technical problem solving, and technology transfer are essential
- BS/BA (required) or MS in Chemistry, Systems, Biomedical or Chemical Engineering, or closely related field with 0-2 years related experience
- Hands-on experience with fermentation, enzymatic reaction, chromatography and/or tangential flow filtration experience is preferred
- Ability to multi-task in relentless pursuit of successful outcomes
- Exceptional written and oral communication
Requirements
- Demonstrated success in bioprocess development, technical problem solving, and technology transfer
- BS/BA (required) or MS in Chemistry, Systems, Biomedical or Chemical Engineering, or closely related field
- 0-2 years related experience
- Hands-on experience with fermentation, enzymatic reaction, chromatography and/or tangential flow filtration is preferred
- Ability to multi-task
- Exceptional written and oral communication
Benefits
- Competitive healthcare
- Voluntary benefit programs
- Fitness support
- Mindfulness support
- Mental health support
- Fertility support
- Adoption support
- Surrogacy support
- Paid time off
- Volunteer days
- Sabbatical
- Global recharge days
- Year-end shutdown
- Savings and investments
- Discretionary bonus
- Equity award
Company overview
Moderna, Inc. is a pioneering American biotechnology and pharmaceutical company headquartered in Cambridge, Massachusetts, that has revolutionized the field of medicine through its groundbreaking messenger RNA (mRNA) technology. Founded in 2010, the company has established itself as a global leader in RNA therapeutics, primarily focusing on mRNA vaccines and treatments. Moderna's innovative platform uses mRNA to provide cellular instructions for producing proteins that trigger immune responses, creating a new category of medicines with significant potential to improve patient outcomes across various therapeutic areas. The company gained worldwide recognition during the COVID-19 pandemic for developing one of the earliest and most effective mRNA vaccines, which demonstrated the transformative potential of its technology platform. Beyond infectious diseases, Moderna is advancing a diverse pipeline of 44 treatment and vaccine candidates across infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases, and autoimmune conditions. With approximately 5,800 employees and a strong commitment to scientific innovation, Moderna continues to expand its manufacturing capabilities and research initiatives to deliver the greatest possible impact through mRNA medicines.