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Exec Dir Enterprise Architect

Regeneron Pharmaceuticals

Sleepy Hollow, NY; Warren, NJOnsitePosted 47 days ago$285,600 - $475,900/year
Full TimeDirector & AboveTech & Data (Health IT)Biotechnology
Original posting ↗

Summary

This role leads Enterprise Architecture for the organization, setting the technology vision, standards, and governance that align business strategy with scalable, secure, and future-ready technology platforms. The Executive Director partners with senior IT and business leadership to shape the enterprise technology roadmap, drive architecture decision-making across data, cloud and infrastructure, application, and integration domains, and ensure technology investments deliver measurable business value. This is both a strategic and hands-on leadership role, requiring the ability to influence at the executive level while maintaining the technical depth to guide complex, enterprise-wide architecture decisions, and to build and mentor a high-performing architecture organization.

Job description

Enterprise Architecture Strategy & Vision

  • Define and own the enterprise architecture strategy, principles, and target-state blueprints across the data, cloud and infrastructure, application, and integration domains, incorporating security and AI architecture standards set in partnership with the CISO and CAIO organizations.
  • Translate business strategy and digital transformation priorities into a coherent, multi-year enterprise technology roadmap.
  • Establish and evolve the enterprise's architecture operating model, ensuring architecture decisions scale with business growth and complexity.
  • Assess emerging technology trends (AI/ML, cloud-native platforms, automation) and determine their strategic fit and adoption path for the enterprise.
  • Champion a "business capability first" architecture approach, ensuring technology investments map directly to business outcomes.

Architecture Governance & Standards

  • Establish and lead the enterprise architecture governance framework, including review boards, design authority processes, and exception management.
  • Define and enforce enterprise architecture standards, patterns, and reference architectures across build, buy, and integrate decisions.
  • Own the architecture review process for major programs and capital investments, ensuring alignment with enterprise standards, security, and regulatory requirements.
  • Maintain the enterprise architecture repository (current-state and future-state models, technology inventories, and roadmaps) as an authoritative source of truth.
  • Partner with Security, Risk, and Compliance to ensure architecture decisions meet enterprise risk tolerance and regulatory obligations (e.g., GxP, data privacy).

Technology Roadmap & Investment Planning

  • Lead enterprise-wide technology rationalization efforts, identifying opportunities to consolidate, retire, or modernize legacy platforms.
  • Partner with Finance and business unit leaders to build the business case for architecture-driven investments, balancing innovation with cost discipline.
  • Guide platform and vendor selection decisions for enterprise-critical systems, ensuring architectural fit, scalability, and total cost of ownership are fully evaluated.
  • Own the enterprise's cloud and infrastructure strategy, ensuring architecture decisions support performance, resilience, and cost efficiency at scale.
  • Drive the integration architecture strategy across the enterprise, enabling seamless data flow and interoperability between core business systems.

Business & Digital Transformation Partnership

  • Serve as a trusted architecture advisor to business unit leaders, translating business problems into technology-enabled solutions.
  • Partner with product, engineering, and program leadership to embed architecture thinking early in the delivery lifecycle, reducing rework and technical debt.
  • Lead architecture input into major digital transformation and modernization initiatives, ensuring solutions are designed for scale, security, and long-term maintainability.
  • Evaluate and guide the adoption of AI, automation, and data platforms to accelerate business capabilities and competitive differentiation.
  • Act as an escalation point for cross-functional architecture conflicts, driving resolution through data-driven, business-aligned decision-making.

Solution & Platform Architecture Oversight

  • Provide senior oversight and quality assurance for solution architectures developed by domain and solution architects across the enterprise.
  • Ensure architectural consistency and reuse across programs, preventing siloed or duplicative technology investments.
  • Guide the design of resilient, secure, and scalable platform architectures for enterprise applications, data platforms, and integration layers.
  • Champion architecture practices that support DevOps, CI/CD, and infrastructure-as-code adoption across delivery teams.
  • Oversee technical due diligence for mergers, acquisitions, and strategic partnerships, assessing architectural risk and integration complexity.

Executive Stakeholder Engagement & Communication

  • Present enterprise architecture strategy, roadmaps, and investment recommendations to executive leadership, technology governance forums, as needed.
  • Build strong, trusted relationships with the Digital and Technology Leadership, and business unit executives to ensure architecture remains a strategic partner, not a bottleneck.
  • Communicate complex technical concepts and trade-offs in clear, business-relevant terms to non-technical executive audiences.
  • Represent the enterprise architecture function in vendor, industry, and partner forums, staying current on best practices and market direction.
  • Establish and sustain the operating model for collaboration with the CISO and CAIO organizations' own architecture teams — defining clear decision rights, escalation paths, and shared standards so security and AI architecture decisions remain aligned to enterprise architecture without duplicated ownership.
  • Partner with the business strategy function that owns business architecture, ensuring enterprise technology roadmaps remain traceable to business capability models maintained outside Digital and Technology.

People Leadership, Mentoring & Team Culture

  • Build, lead, and develop a high-performing architecture team, directly leading the Data & AI, Cloud & Infrastructure, Application, and Integration Domain Architects, and fostering a culture of technical excellence and collaboration.
  • Mentor and coach architects and senior technical leaders, investing in career growth, technical depth, and succession planning.
  • Establish architecture communities of practice and knowledge-sharing forums that elevate architecture maturity across the broader technology organization.
  • Champion diversity, equity, and inclusion in hiring, development, and team culture within the architecture function.
  • Model and reinforce a culture of intellectual curiosity, pragmatism, and accountability across the architecture team.

Technical Competencies

  • Deep expertise in enterprise architecture frameworks and methodologies (TOGAF, Zachman, or equivalent) and their practical application in a large, complex organization.
  • Strong technical grounding across cloud platforms (AWS, Azure, GCP), enterprise integration, data architecture, and application architecture patterns.
  • Strong grounding in enterprise integration architecture — API management, event-driven patterns, and integration platform strategy.
  • Working knowledge of AI/ML platforms, data and analytics architecture, and emerging technology evaluation.
  • Experience with enterprise security architecture, identity and access management, and regulatory/compliance frameworks relevant to the industry (e.g., GxP, data privacy).
  • Familiarity with modern software delivery practices — DevOps, CI/CD, microservices, and infrastructure-as-code.

Leadership & People Skills

  • Proven ability to build, scale, and lead high-performing architecture teams, including hiring, developing, and retaining top technical talent.
  • Experience leading architecture functions within a global, matrixed organization, including geographically distributed teams.
  • Ability to mentor and grow architects and technical leaders, building bench strength and succession depth.
  • Experience establishing and sustaining a collaborative operating model with peer architecture functions (e.g., the CISO's and CAIO's own architecture teams), ensuring clear accountability without duplicated ownership.

Strategic & Business Skills

  • Strong business acumen and the ability to translate business strategy into a coherent, executable technology roadmap.
  • Sound judgment in balancing innovation, risk, cost, and speed to market in architecture decision-making.
  • Ability to lead through ambiguity, structuring clear technology direction from complex or evolving business requirements.

Communication & Stakeholder Abilities

  • Executive presence and the ability to influence and communicate effectively with senior business and technology leaders, including at the EVP and possibly the board level.
  • Ability to translate complex technical topics into clear, business-relevant narratives for non-technical audiences.
  • Strong collaboration skills across global, cross-functional, and cross-cultural stakeholder groups.

Requirements

  • Bachelor's degree in Computer Science, Information Technology, Engineering, or a related field is required.
  • A Master's degree or MBA is strongly preferred.
  • 17+ years of progressive experience in enterprise architecture, IT strategy, or technology leadership roles.
  • 10+ years in senior leadership roles guiding architecture, engineering, or technology strategy teams within a large, complex, global organization.

Requirements

  • Bachelor's degree in Computer Science, Information Technology, Engineering, or a related field is required.
  • A Master's degree or MBA is strongly preferred.
  • 17+ years of progressive experience in enterprise architecture, IT strategy, or technology leadership roles.
  • 10+ years in senior leadership roles guiding architecture, engineering, or technology strategy teams within a large, complex, global organization.
  • Deep expertise in enterprise architecture frameworks and methodologies (TOGAF, Zachman, or equivalent).
  • Strong technical grounding across cloud platforms (AWS, Azure, GCP), enterprise integration, data architecture, and application architecture patterns.
  • Strong grounding in enterprise integration architecture — API management, event-driven patterns, and integration platform strategy.
  • Working knowledge of AI/ML platforms, data and analytics architecture, and emerging technology evaluation.
  • Experience with enterprise security architecture, identity and access management, and regulatory/compliance frameworks (e.g., GxP, data privacy).
  • Familiarity with modern software delivery practices — DevOps, CI/CD, microservices, and infrastructure-as-code.
  • Proven ability to build, scale, and lead high-performing architecture teams.
  • Experience leading architecture functions within a global, matrixed organization, including geographically distributed teams.
  • Executive presence and the ability to influence and communicate effectively with senior business and technology leaders.

Benefits

  • Annual bonuses
  • Incentive plans
  • Equity awards
  • Pension or retirement benefits
  • 401(k) company match
  • Health and wellness programs
  • Fitness centers
  • Medical, Dental & Vision
  • Life and disability insurance
  • Paid time off
  • Family support benefits
  • Relocation benefits

Company overview

Regeneron Pharmaceuticals is a leading American biotechnology company founded in 1988 and headquartered in Tarrytown, New York. The company specializes in inventing, developing, and commercializing life-transforming medicines for people with serious diseases. Regeneron is renowned for its innovative antibody technologies and has developed several groundbreaking therapies, including EYLEA® for retinal diseases, DUPIXENT® for inflammatory conditions, and the COVID-19 antibody cocktail REGEN-COV®. The company operates with a strong focus on research and development across multiple therapeutic areas including ophthalmology, oncology, cardiovascular diseases, and rare genetic disorders. Regeneron's proprietary VelocImmune® technology platform enables the rapid generation of fully human monoclonal antibodies. With over 15,000 employees globally and annual revenues exceeding $14 billion, Regeneron has established itself as a major force in the biotechnology industry, consistently ranking among the top-performing pharmaceutical companies and maintaining a robust pipeline of investigational therapies.

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