Executive Director, Clinical Science, Immunology

Position Overview

The Executive Director, Clinical Science is a senior leader within Non-Oncology Clinical Development responsible for providing strategic, scientific, operational, and people leadership across a portfolio of immunology programs spanning multiple stages of development. Reporting to the Head of Clinical Science Non-Oncology, this role serves as a member of the Clinical Science Leadership Team and plays a key role in shaping the strategic direction, operational effectiveness, and long-term growth of the Clinical Science organization.

The Executive Director leads a large organization of Clinical Scientists supporting immunology development programs and is accountable for portfolio delivery, organizational performance, talent development, capability building, and continuous improvement. This leader ensures the highest standards of scientific rigor, patient focus, quality, and regulatory readiness while driving consistency and excellence across Clinical Science activities.

Key Responsibilities

Portfolio Leadership

• Holds accountability for portfolio delivery from the Clinical Science perspective, including prioritization, resource alignment, and support for key development milestones across studies, programs, and assets.
• Provide strategic oversight for a portfolio of immunology assets across multiple stages of development.
• Partner with the Immunology Therapeutic Area Head and leaders across Clinical Operations, Regulatory Affairs, Biostatistics and Data Management, Drug Safety and Pharmacovigilance, Translational Medicine, and Medical Affairs to drive development strategy execution and delivery of key portfolio milestones.
• Ensure Clinical Science contributions support development plans, regulatory submissions, health authority interactions, and lifecycle management activities.
• Apply Clinical Science expertise to inform therapeutic area and portfolio strategy across evolving science, treatment trends, competitive landscape, and regulatory considerations.
• Optimize allocation of Clinical Science resources and associated budgets across a complex and evolving portfolio to align with business priorities and organizational objectives.
• Serve as a senior escalation point for scientific and resource-related issues, enabling effective and timely resolution.

Clinical Science Excellence

• Establish and sustain high standards for scientific rigor, clinical science quality, medical data review, study oversight, and regulatory readiness across the portfolio.
• Drive consistency in clinical science practices, study execution, and data interpretation across therapeutic areas and development programs.
• Foster a culture of proactive risk identification, mitigation, inspection readiness, and continuous quality improvement.
• Advance innovative approaches to medical data review, signal detection, study oversight, and evidence-based decision-making that enhance development outcomes.

Innovation, AI, and Digital Transformation

• Champion adoption of AI-enabled, digital, and technology-driven capabilities that enhance Clinical Science productivity, quality, efficiency, and effectiveness.
• Contribute to identifying opportunities to leverage advanced analytics, artificial intelligence, automation, and digital solutions to improve decision-making, strengthen study oversight, and streamline workflows.
• Drive modernization of clinical data review through innovative approaches that enhance insight generation and support timely, informed decisions.
• Foster a culture of innovation, experimentation, continuous learning, and responsible implementation of emerging technologies.
• Partner with cross-functional stakeholders to define, develop, and implement scalable capabilities that support future organizational needs and long-term business success.

People Leadership and Talent Development

• Lead, coach, and develop a high-performing Clinical Science organization.
• Build organizational capability through talent planning, succession management, leadership development, and career growth strategies.
• Create an inclusive environment that promotes engagement, psychological safety, accountability, collaboration, and continuous development.
• Develop future leaders by mentoring Clinical Scientists, strengthening scientific, strategic, and leadership capabilities across the organization.
• Ensure leaders are equipped to provide effective coaching, feedback, performance development, and career support for their teams.

Organizational Leadership

• Contribute to the development and execution of Clinical Science strategy, priorities, and long-term organizational objectives.
• Lead initiatives related to organizational design, workforce planning, and resource optimization to support evolving portfolio and business needs.
• Develop and implement scalable operating models that balance portfolio execution, organizational effectiveness, employee development, and talent retention.
• Lead cross-functional initiatives that improve efficiency, effectiveness, innovation, and organizational health.
• Represent Clinical Science in governance forums, leadership discussions, and strategic planning activities.
• Shape functional and enterprise priorities through leadership engagement, cross-functional partnerships, and influence across organizational boundaries.