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Executive Director, U.S. HCP Marketing

Madrigal Pharmaceuticals

Conshohocken, PA; Waltham, MAOnsitePosted 46 days ago$300,282 - $345,264 per year
Full TimeDirector & AboveCommercial & Pharma SalesPharmaceutical
Original posting ↗

Summary

Madrigal is seeking an Executive Director, U.S. HCP Marketing for Rezdiffra, to shape and actualize the HCP marketing strategy for Rezdiffra and the broader MASH therapeutic category. This role is a high-visibility role for a leader who can shape brand and content strategy while being comfortable with a roll your sleeves up approach in tactical development and execution.

Job description

Key Responsibilities

Strategic Leadership

  • Own the HCP marketing strategy and contribute to the development of the annual global brand plan for Rezdiffra, aligning tactics to lifecycle stage, competitive dynamics, and portfolio priorities.
  • Translate market research, prescriber analytics, and customer feedback into a clear, differentiated brand positioning and messaging framework for HCP audiences.
  • Anticipate and plan for competitive threats (new entrants, label expansions) and adjust HCP strategy accordingly.

Campaign & Content Development

  • Lead development of core and derivative promotional tools and continue to evolve promotional claims beyond label by leveraging FDA's CFL guidance.
  • Oversee non-personal promotion (NPP) strategy across peer-to-peer channels, paid media, and programmatic/digital channels targeting HCPs.
  • Ensure all materials are scientifically accurate, on-label, and approved through Promotional Review Committee (PRC) composed of Medical, Legal, and Regulatory.

KOL & Congress Strategy

  • Develop and manage KOL engagement strategy in partnership with Thought Leader Liaison team, Medical Affairs, and Sales including oversight of advisory boards and promotional speaker bureau.
  • Own planning and execution for major medical congresses and conferences (booth strategy, product theaters, print and digital sponsorships).

Sales Enablement

  • Serve as the primary marketing partner to Sales Leadership; ensure each field team is equipped with compelling, compliant tools and messaging.
  • Partner closely with Commercial training and development for implementation of new tools and messaging during and outside of planned national and regional sales meetings.

Omni-channel/non-personal promotion

  • Lead the transformation from traditional campaign-based marketing to AI-driven, dynamic engagement models by championing the use of customer-centric analytics to deliver personalized customer approaches across channels.
  • Partner with Commercial Strategy and Analytics and appropriate external vendors to build and monitor performance dashboards (Rx trends, NPS, share of voice, digital engagement).
  • Monitor marketing mix effectiveness and use insights to optimize strategies and tactics.

Cross-Functional Collaboration

  • Collaborate with Patient Marketing counterparts to ensure a unified HCP-to-patient journey.
  • Cultivate strong working partnerships with Sales, Thought Leader Liaison, Commercial Strategy and Analytics, Market Access and Patient Services to ensure a cohesive brand story.
  • Work closely with Regulatory and Legal/Compliance to navigate promotional review and ensure adherence to PhRMA Code, FDA regulations (OPDP), and company SOPs.

Team Leadership & Operations

  • Hire, coach, and develop high-performing HCP marketing team.
  • Own HCP marketing budget tracking, forecasting, and reconciliation.
  • Manage relationships with external agencies (creative, media, medical communications) to ensure high-quality, on-time, on-budget deliverables.
  • Prepare regular reports for commercial and executive leadership team on progress, challenges, and recommendations.

Required Qualifications

  • Bachelor's degree required; MBA or advanced degree preferred.
  • 18+ years of pharmaceutical/biotech marketing experience, with 10+ years in HCP-facing brand marketing roles of increasing responsibility with a majority of experience on a specialty brand.
  • Experience in liver and/or a cardiometabolic therapy preferred.
  • Proven experience marketing a blockbuster or high-growth/high-potential specialty product.
  • Demonstrated success building and actualizing HCP marketing strategy within constraints and processes mandated by a Subpart H (conditional approval).
  • Demonstrated experience as a people leader managing and leading Marketing professionals.
  • Excellent cross-functional collaboration skills, particularly with Sales, Thought Leader Liaisons, Medical Affairs, Market Access, and Legal/Regulatory.
  • Ability to distill complex information into essential knowledge and persuasively present it to all levels of management.
  • Strong interpersonal skills, including the ability to lead, identify and resolve conflict, and drive consensus among individuals from a variety of viewpoints and disciplines.
  • Role requires up to 30% US travel.

Requirements

  • Bachelor's degree required
  • 18+ years of pharmaceutical/biotech marketing experience
  • 10+ years in HCP-facing brand marketing roles
  • Experience marketing a blockbuster or high-growth/high-potential specialty product
  • Demonstrated success building and actualizing HCP marketing strategy within Subpart H constraints
  • Demonstrated experience as a people leader managing Marketing professionals
  • Excellent cross-functional collaboration skills
  • Ability to distill complex information and present to all levels of management
  • Strong interpersonal skills including conflict resolution and consensus building
  • Up to 30% US travel

Benefits

  • Equity
  • 401(k) Matching
  • Flexible PTO
  • Medical, Dental & Vision
  • Life & Disability Insurance
  • Mental Health Benefits
  • Employee Assistance Program
  • Supplemental Life Insurance
  • Legal Services

Company overview

Madrigal Pharmaceuticals, Inc. is a clinical-stage biopharmaceutical company focused on developing novel therapeutics for metabolic dysfunction-associated steatohepatitis (MASH), formerly known as non-alcoholic steatohepatitis (NASH), a serious form of fatty liver disease. The company's lead product, Rezdiffra (resmetirom), is a once-daily, oral thyroid hormone receptor (THR)-β selective agonist that targets key underlying causes of MASH in the liver. Rezdiffra received FDA approval in 2024 as the first treatment for MASH with moderate to advanced liver fibrosis, representing a significant breakthrough in hepatology. Headquartered in Conshohocken, Pennsylvania, Madrigal is publicly traded on NASDAQ under the symbol MDGL. The company continues to advance its clinical development programs, including ongoing Phase 3 trials evaluating Rezdiffra for the treatment of compensated MASH cirrhosis. Madrigal's innovative approach addresses a critical unmet medical need in liver disease therapeutics.

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