Global Clinical Program Lead, Hematology
AstraZeneca
Summary
AstraZeneca Hematology R&D is seeking a Global Clinical Program Lead (GCPL) to lead the clinical development and execution of product strategy for multiple projects, reporting to the Global Clinical Head of the disease indication.
Job description
Responsibilities
- Leads clinical development teams responsible for novel Hematology Oncology therapies from preclinical candidate selection through proof of concept leading to Phase 3 investment decisions.
- Leads all regulatory submissions.
- Accountable for the clinical strategy and clinical execution of a portfolio of pre-clinical and clinical stage therapies.
- Accountable for the delivery of projects according to quality, time, budgets and resources.
- Builds strategic and coordinated clinical development plans aligned with business objectives and differentiated from competitor products.
- Leads and communicates the clinical development strategy at governance meetings and with external collaborators.
- Leads clinical aspects of projects from preclinical Lead Optimization Investment Decision to clinical Proof of Concept, including translational, clinical development, patient selection, regulatory, pediatric, and Asian development strategy.
- Develops the Target Product Profile, ensuring alignment with disease area strategy and late stage development.
- Co-leads the Clinical Program Team (CPT) to run/mitigate/communicate risk, make decisions, and handle conflict and change.
- Maintains a high degree of CPT effectiveness through collaboration, influence, and coaching/mentoring of cross-functional team members.
- Ensures robust processes, plans and data enable Governance Bodies to make investment decisions and prioritize projects across the portfolio.
Minimum Qualifications
- M.D. is required
- A minimum of 7 years of relevant experience
- Industry experience in drug development including early and late phase drug development and regulatory knowledge
- Strong knowledge and understanding of the Hematology Oncology therapeutic area with experience in diverse biological mechanisms
- Broad understanding of the evolving clinical landscape in hematology/oncology
- Proven experience mentoring and motivating teams in a highly matrixed environment
- Proven record of encouraging and leading internal and external cross-functional collaborations
- Demonstrated organizational and project management skills
- Proven success in influencing colleagues and senior leaders in various departments
- Must demonstrate high integrity
Requirements
- M.D. is required
- A minimum of 7 years of relevant experience
- Industry experience in drug development including early and late phase drug development and regulatory knowledge
- Strong knowledge and understanding of the Hematology Oncology therapeutic area with experience in diverse biological mechanisms
- Broad understanding of the evolving clinical landscape in hematology/oncology
- Proven experience mentoring and motivating teams in a highly matrixed environment
- Proven record of encouraging and leading internal and external cross-functional collaborations
- Demonstrated organizational and project management skills
- Proven success in influencing colleagues and senior leaders in various departments
- Must demonstrate high integrity
Benefits
- 401(k) Matching
- Paid Vacation
- Paid Holidays
- Paid Leaves
- Medical, Dental & Vision
- Prescription Drug Coverage
- Short-Term Incentive Bonus
- Equity-Based Long-Term Incentive
- Retirement Contribution
Company overview
AstraZeneca is a global, science-led, patient-focused pharmaceutical company dedicated to accelerating the delivery of life-changing medicines that create enduring value for patients, society, and shareholders. With a workforce of over 94,300 employees worldwide, the company operates across three core therapy areas: Oncology, BioPharmaceuticals (including Cardiovascular, Renal & Metabolism, Respiratory & Immunology), and Rare Disease. Headquartered in Cambridge, UK, AstraZeneca maintains strategic R&D centers in Cambridge, Gaithersburg (US), Boston (US), Gothenburg (Sweden), Shanghai, and Beijing. The company generated $54.1 billion in total revenue in 2024 and invested $13.6 billion in scientific research and development. AstraZeneca's bold aspiration is to be pioneers in science, lead in disease areas, and transform patient outcomes, with a goal to launch 20 new medicines and achieve $80 billion in total revenue by 2030. The company is recognized for its commitment to sustainability, health equity, and creating an inclusive work environment where diverse perspectives drive innovation.