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Intern, FFBA Analytical Development

Legend Biotech US

Somerset, NJOnsitePosted 11 days ago
InternshipInternResearch & ScientistBiotechnology
Original posting ↗

Summary

We are seeking an enthusiastic and driven Intern to join Functional, Flow Cytometry and BioAnalytics team within our empowered Analytical Development organization. The intern will focus on supporting the development of novel flow cytometry-based methods to assess cellular metabolism in immune and engineered cell products. The project will focus on establishing robust essays to characterize metabolic states of t cells transduced with LB2501 LVV. Working closely with principal scientists in Analytical Development, the candidate will design experiments, optimize staining panels, analyze multiparametric flow cytometry data, and documentation.

Job description

Role Overview

We are seeking an enthusiastic and driven Intern to join Functional, Flow Cytometry and BioAnalytics team within our empowered Analytical Development organization. The intern will focus on supporting the development of novel flow cytometry-based methods to assess cellular metabolism in immune and engineered cell products. The project will focus on establishing robust essays to characterize metabolic states of t cells transduced with LB2501 LVV. Working closely with principal scientists in Analytical Development, the candidate will design experiments, optimize staining panels, analyze multiparametric flow cytometry data, and documentation.

Key Responsibilities

  • Collaborate with scientists to identify pain points in the electronic sample ascension process.
  • Develop and draft procedures to streamline and organize sample data and test reporting.
  • Observe and assist with routine testing of non-critical samples.
  • Perform routine laboratory activities, like equipment calibration, cleaning, and general laboratory upkeep.
  • Assist in the creation of accurate Electronic Laboratory Notebook entries and LIMS sample templates.

This is a closely mentored role, and most decisions about planning and execution will require collaboration, consensus and alignment with senior scientists.

Requirements

  • Undergraduate or master's student in Immunology, Cell Biology, Molecular Biology, Biomedical Engineering, Biochemistry, or Biotechnology
  • Strong written and verbal English skills
  • Authorized to work in the United States
  • Preferred experience with mammalian cell culture
  • Preferred experience with flow cytometry
  • Preferred experience with fluorescence-based assays
  • Preferred experience with data analysis software
  • Preferred experience with basic statistics
  • Strong analytical thinking
  • Attention to detail
  • Scientific curiosity
  • Effective communication
  • Microsoft Office Suite
  • GraphPad Prism, PowerBI, JMP, R

Company overview

Legend Biotech is a global, commercial-stage biotechnology company specializing in the development and manufacturing of advanced cell therapies. Headquartered in Somerset, New Jersey, the company was founded in 2014 and has grown to become a leader in the cell therapy space with over 2,600 employees worldwide. Legend Biotech focuses on innovative cellular immunotherapy platforms, including autologous and allogeneic chimeric antigen receptor T-cell (CAR-T) therapies, natural killer (NK) cell-based immunotherapies, and non-gene-editing universal CAR-T technologies. The company's flagship product, CARVYKTI® (ciltacabtagene autoleucel), developed in collaboration with Johnson & Johnson, is a BCMA-directed CAR-T therapy approved for the treatment of relapsed or refractory multiple myeloma. With a robust pipeline of 11 investigational therapies spanning multiple disease areas, Legend Biotech operates research and development facilities across the United States, Europe, and China, maintaining a strong commitment to transforming patient care through cutting-edge cellular therapies.

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