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Intern - Machine Learning for Neuroscience

Allen Institute

Seattle, WAHybridPosted 5 days ago$38.00/hour
InternshipInternBioinformatics & Data ScienceResearch Institute
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Summary

12 Month Duration - starting late fall 2026

Job description

Research Intern – Machine Learning for Neuroscience

12 Month Duration - starting late fall 2026

The goal of the Neural Dynamics accelerator is to understand how the brain generates flexible behavior. We aim to uncover the algorithms—implemented by dynamics in brain-wide neural circuits—that allow animals to build internal models, process information, and choose actions.

We are searching for a graduate student intern who will analyze large-scale neural and behavioral recordings to uncover how populations of neurons coordinate to control movement.

This is a one-year, part-time research position at the intersection of machine learning and neuroscience. The intern will work with a rich existing dataset: two intermingled but genetically distinct populations of neurons in the striatum, recorded simultaneously, with individual cells tracked stably across many days, alongside a continuously measured motor output and synchronized muscle activity and video. The central question is a latent-variable modeling problem — how do the two populations jointly encode the motor output, and how much of their activity is shared between them versus private to each? No prior neuroscience background is required; the intern will be mentored directly. The position is a one-year commitment so that the intern has time to carry a project through to a scientific result, and strong work may contribute to a conference presentation or publication.

Essential Functions

  • Characterize how coordinated activity across two simultaneously recorded neural populations encodes forelimb force
  • Implement, fit, and evaluate machine learning and latent variable models that partition shared versus population-specific covariance, and benchmark them against recently published alternatives
  • Relate neural population activity to behavioral variables using regression and classification methods, with appropriate cross-validation and controls
  • Extend the analysis to electromyography (EMG) and synchronized behavioral video, and to how neural coding and behavior change across days of learning
  • Produce documented, version-controlled Python analysis code that other team members can build on
  • Communicate results to the mentoring scientists and the wider team, and contribute figures and methods text toward posters and manuscripts

Educational Objectives

  • Hands-on experience applying machine learning and signal processing methods to large-scale neural and behavioral datasets
  • Practical understanding of latent variable and dimensionality reduction models for multi-population data
  • Experience with reproducible, collaborative scientific computing and open science practices
  • Direct mentorship from staff scientists, exposure to systems neuroscience as a research area, and development of scientific writing and presentation skills

Required Education And Experience

  • Currently enrolled in a master’s or PhD program in electrical and computer engineering, computer science, or a related quantitative field
  • Completed coursework, prior to the start of the position, in programming, linear algebra, probability and statistics, and at least one of machine learning or signal processing
  • Demonstrated experience with scientific computing in Python (numpy, scipy, pandas)
  • Available to start in late October / early November 2026 and able to commit to the position for one year
  • Able to work onsite at least one day per week

Preferred Education And Experience

  • Coursework or project experience with linear regression and discrete classifiers (e.g., support vector machines)
  • Coursework or project experience with dimensionality reduction and latent variable models (e.g., PCA, factor analysis, canonical correlation analysis)
  • Experience with time series analysis and signal processing (filtering, spectral methods)
  • Experience with scikit-learn and with deep learning frameworks such as PyTorch
  • Experience with video-based pose estimation tools (e.g., DeepLabCut, SLEAP, Lightning Pose) or with biosignal analysis such as EMG
  • Experience with software best practices (version control, code review, testing)
  • Interest in computational or systems neuroscience; prior neuroscience coursework or research is welcome but not required
  • Strong written and verbal communication skills, and the ability to work both independently and in a collaborative, multi-disciplinary environment

Requirements

  • Currently enrolled in a master’s or PhD program in electrical and computer engineering, computer science, or a related quantitative field
  • Completed coursework in programming, linear algebra, probability and statistics, and at least one of machine learning or signal processing
  • Demonstrated experience with scientific computing in Python (numpy, scipy, pandas)
  • Available to start in late October / early November 2026 and able to commit to the position for one year
  • Able to work onsite at least one day per week

Benefits

  • Hybrid work environment
  • Flexible weekly hours
  • Academic credit possible

Company overview

The Allen Institute is a premier non-profit research organization founded in 2003 by philanthropist Paul G. Allen, co-founder of Microsoft. Headquartered in Seattle, Washington, the institute is dedicated to answering fundamental questions in biology and accelerating scientific discovery through large-scale, collaborative research projects. The organization operates several major research divisions including the Allen Institute for Brain Science, Allen Institute for Cell Science, and Allen Institute for Immunology. The Allen Institute is renowned for creating comprehensive, open-access data resources and tools for the global scientific community, such as the Allen Brain Atlas, which provides detailed maps of gene expression in the mouse and human brain. Their research approach combines experimental biology with computational analysis and data science to generate transformative insights into complex biological systems. The institute's work has significantly advanced understanding of brain function, cellular biology, and immune system dynamics, making it a leading force in modern biomedical research with a strong commitment to open science and data sharing.

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