Lab, Clinical Research Scientist
Castle Biosciences
Summary
As a Clinical Research Scientist, you will serve as a primary technical resource for assay-related troubleshooting, data review, feasibility assessments, and testing questions. You will work closely with R&D when new samples, study concepts, or potential projects are introduced, helping translate those ideas into practical protocols and effective data-collection plans.
Job description
A key part of the role is determining how proposed methods can be performed consistently, scaled appropriately, and ultimately incorporated into a clinical laboratory environment. This includes reviewing results, investigating unexpected findings, optimizing workflows, developing and maintaining SOPs, supporting instrument verification and assay validation activities, and providing technical guidance to laboratory personnel.
You will collaborate with R&D, laboratory operations, quality, regulatory, and other cross-functional teams to ensure that studies are scientifically sound and operationally practical. You may also contribute to regulatory documentation and assay submissions, although regulatory writing is not the primary focus of the position.
Schedule
Monday - Friday, exempt position, working from our Scottsdale, AZ laboratory.
Requirements
- Bachelors in Life Science, Biology, or Clinical Laboratory Science and 4-7 years research/development experience
- Or Master's and 3-5 years of experience or PhD and 1-2 years of experience
- Demonstrated technical proficiency, scientific creativity, successful collaboration with others, and independent thought
- Minimum 4 years laboratory experience in High Complexity testing plus QA training or 2 years clinical QA experience
- Experience with one or more of the following: Molecular techniques, digital imaging, multiplex immunolabeling, digital pathology, image analysis or processing, bioinformatics/computational biology
- All candidates must be legally authorized to work in the United States
Benefits
- Annual salary
- 20% bonus potential
- 20 accrued PTO days
- 10 paid holidays
- 401(k) with 100% match up to 6%
- 3 health care plan options
- Company HSA contribution
- Company stock grant
Company overview
Castle Biosciences (Nasdaq: CSTL) is a leading molecular diagnostics company that develops and commercializes innovative tests to guide patient care decisions. Founded in 2008 and headquartered in Friendswood, Texas, the company focuses primarily on dermatologic and gastroenterological diseases, with a mission to transform disease management through personalized, clinically actionable solutions. Castle's proprietary portfolio includes five commercial tests targeting unmet clinical needs in dermatologic cancers, Barrett's esophagus, and uveal melanoma. Their flagship product, DecisionDx®-Melanoma, is a gene expression profile test that predicts metastasis risk in cutaneous melanoma patients. The company also markets TissueCypher® for Barrett's esophagus, DecisionDx®-SCC for squamous cell carcinoma, MyPath® Melanoma for lesion characterization, and DecisionDx®-UM for uveal melanoma staging. With laboratory operations in Phoenix, Arizona and Pittsburgh, Pennsylvania, Castle Biosciences employs advanced molecular technologies to provide physicians with objective data for more confident treatment planning. The company reported $83 million in Q3 2025 revenue and has demonstrated strong growth in its core testing franchises, positioning itself as a significant player in the precision diagnostics market.