LIMS Associate, Oncology
BillionToOne
Summary
We are looking for a LIMS Associate to join our Laboratory Information Management Systems (LIMS) team in support of clinical patient testing in our high-throughput CLIA lab. The LIMS Associate will be responsible for (1) Coordinating tech transfer between the clinical lab and LIMS Engineers, (2) Triaging and responding to support tickets, and closing them out where possible, (3) monitoring LIMS usage patterns, trends, and issues in the lab and suggesting improvements to LIMS developers. This is considered an onsite role at our Menlo Park lab, with flexibility to work from home or at our Union City site when applicable.
Job description
Responsibilities
- Collaborate closely with wet lab scientists in our clinical molecular biology lab to understand workflows and the corresponding data flow needs
- Perform routine LIMS systems and software maintenance procedures
- Collaborate with SMEs to design & implement LIMS workflows & to support new assay launches
- Work with the LIMS Administrator to manage existing LIMS workflows, their operations, lifecycle and data
- Manage full release process, including validation, coordination of training, completion of required documentation, and deployments
- In coordination with the LIMS Administrator, liaise with Semaphore Solutions, the external developer of the Labbit LIMS, and with other third party contractors & developers, as needed
- Monitor, troubleshooting, and correct systems and software technical issues (e.g. resolving bugs and LIMS outages)
- Triage & escalate unresolved technical issues to appropriate internal teams or external developers
- Network with internal stakeholders & customers to develop new technologies
- Develop and maintain relevant technical documentation (SOPs, Policies, etc) for use of BTO's LIMS systems
- Create workflow diagrams and documentation of current and proposed lab processes
- Ensure compliance to all relevant corporate and regulatory requirements
- Collaborate with the LIMS Administrator to provide end-to-end support & ownership for tickets requiring system change
- Train SMEs in Software Engineering, Data Science, and CLIA to understand LIMS API and data warehouse
- Onboard personnel to LIMS and define systems, roles, and responsibilities
- Assist in establishing scope of features based on goals and timelines
- Monitor KPIs for Labbit LIMS and work with LIMS Administrator and lab personnel to ensure timely progress toward company goals
Requirements
- Bachelor's degree in Computer Science, Software or Information Systems or equivalent technical expertise with information systems
- Comfortable working with cross-functional teams across CLIA, Process Engineering, Software Engineering, Automation and Service Engineering, Data Science, Supply Chain, and Product
- Excellent ability to communicate with CLIA lab personnel to understand molecular biology workflows, regulatory compliance needs and real-world laboratory challenges
- 0-2 Years' Experience with Laboratory Information Systems (LIS)
- 0-2 Years' Experience working in a CLIA Lab, medical device, or pharma environment
- Experience with diagramming workflows using tools such as Lucidchart, Visio, etc.
- Ability to troubleshoot and diagnose basic technical issues
- Experience with Bash or similar shell environment
- Experience with Python
- Strong attention to detail and ability to work flexibly and well under given timeframes
- Highly organized, strong written and verbal communicator
- Excellent problem-solving and communication skills
- Strong project management skills and familiarity with project management tools such as Jira, Notion, etc.
Nice-To-Haves
- Experience with Illumina NGS workflows
- Experience with molecular biology workflows in a high-throughput environment
- Experience developing scripting solutions to automation problems in a fast paced/agile setting
- Experience with automated liquid handlers and software integrations
- Familiarity with AWS S3
- Familiarity with cloud applications and with EC2
- Familiarity with structured data types, including JSON
- Experience with REST APIs
- Experience with the Labbit LIMS platform
- Direct experience with multiple LIMS products (Clarity, STARLIMS, Labvantage, Labworks, etc)
- Familiarity with Quality Management Systems such as Arena and with related regulations (CFR 21 Part 11, ISO 13485, etc)
- Experience with data analysis using Excel, SQL, R, and/or Python
- Experience with ticket support in a production environment
- Experience with bioinformatics pipelines
Requirements
- Bachelor's degree in Computer Science, Software or Information Systems or equivalent technical expertise with information systems
- Comfortable working with cross-functional teams across CLIA, Process Engineering, Software Engineering, Automation and Service Engineering, Data Science, Supply Chain, and Product
- Excellent ability to communicate with CLIA lab personnel to understand molecular biology workflows, regulatory compliance needs and real-world laboratory challenges
- 0-2 Years' Experience with Laboratory Information Systems (LIS)
- 0-2 Years' Experience working in a CLIA Lab, medical device, or pharma environment
- Experience with diagramming workflows using tools such as Lucidchart, Visio, etc.
- Ability to troubleshoot and diagnose basic technical issues
- Experience with Bash or similar shell environment
- Experience with Python
- Strong attention to detail and ability to work flexibly and well under given timeframes
- Highly organized, strong written and verbal communicator
- Excellent problem-solving and communication skills
- Strong project management skills and familiarity with project management tools such as Jira, Notion, etc.
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Family Bonding Leave
- Fertility Benefits
- Paid Time Off
- Equity Grants
- Annual Bonus
- On-site Lunches
- Gym Access
- Free EV Charging
Company overview
BillionToOne is a precision diagnostics company headquartered in Menlo Park, California, founded in 2016 with a mission to make molecular diagnostics more accurate, efficient, and accessible. The company has developed a proprietary Quantitative Counting Templates (QCT) molecular counting platform that can accurately count DNA molecules at the single-molecule level, enabling unprecedented sensitivity in disease detection. BillionToOne operates as a publicly traded company on NASDAQ under the symbol BLLN, having completed a successful IPO in 2025. The company's diagnostic platforms include UNITY Complete for non-invasive prenatal testing, which assesses fetal risk for recessive conditions and aneuploidies from a single maternal blood sample, and Northstar oncology products for cancer therapy selection and treatment response monitoring. With over 500 employees and multiple CLIA/CAP accredited laboratories, BillionToOne represents a significant advancement in quantitative molecular diagnostics, combining breakthrough science with scalable commercial operations to transform healthcare delivery.