Manufacturing Supervisor – Downstream Bioprocessing (Night Shift)
Elanco
Summary
The Manufacturing Supervisor – Downstream Bioprocessing is responsible for leading manufacturing personnel and daily operations supporting the bulk production of monoclonal antibody (mAb) products at Elanco's Elwood, Kansas manufacturing site. This role oversees production activities across downstream bioprocessing operations, ensuring production targets are achieved while maintaining the highest standards of safety, quality, regulatory compliance, and Good Manufacturing Practices (cGMP). The supervisor also plays a key role in developing team members, driving operational excellence, and fostering a culture of accountability and continuous improvement.
Job description
Your Responsibilities
- Lead and oversee daily manufacturing operations supporting downstream bioprocessing activities, including buffer formulation, cell clarification, protein A chromatography, and Tangential Flow Filtration, while partnering with upstream and fill/finish and ensuring adherence to production schedules.
- Supervise, coach, and develop manufacturing personnel through performance management, training, and regular feedback to build a high-performing, engaged team.
- Ensure manufacturing activities are performed in compliance with USDA, EMA, and cGMP requirements, approved procedures, and batch production records.
- Maintain a strong presence on the production floor to promote safe work practices, operational excellence, and a culture of quality and accountability.
- Coordinate with Quality, Engineering, Maintenance, Validation, Supply Chain, and other cross-functional teams to support compliant and efficient manufacturing operations.
- Monitor production performance, equipment readiness, and schedule adherence while ensuring timely completion of batch records, SAP transactions, and manufacturing documentation.
- Lead or support investigations, root cause analyses, and corrective and preventive actions (CAPA) for operational events, deviations, and equipment or process issues.
- Drive continuous improvement initiatives that enhance manufacturing efficiency, strengthen compliance, and improve overall operational performance.
What You Need to Succeed (minimum qualifications)
- Education: Highschool diploma or equivalent
- Experience: 3+ years experience in a regulated, commercial manufacturing environment.
- Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas.
What will give you a competitive edge (preferred qualifications)
- Bachelor's degree in biomanufacturing related field
- Biomanufacturing experience
- Monoclonal antibody manufacturing
- Understanding of USDA, FDA, EU GMP, cGMP regulatory standards
- Operational excellence, lean manufacturing, six sigma, TPS experience
- Demonstrated success in leadership
- Experience with SAP, OSI PI, VEEVA
Additional Information
- Travel: minimal 0-5%
- Location: Elwood, KS
- This role is a night shift 5p-5a 12 hour, 2 week rotation. (M,T,F,Sa,Su,W,R)
- Shift structure is subject to change with notice according to business demands
- Premiums available for night and weekend work
- 10% night weekday, 14% night weekend
Requirements
- High school diploma or equivalent
- 3+ years experience in a regulated, commercial manufacturing environment
- Must be able to wear appropriate gowning and personal protective equipment in manufacturing and support areas
Benefits
- 8-week parental leave
- 9 Employee Resource Groups
- Annual bonus offering
- Up to 6% 401K matching
Company overview
Elanco Animal Health Incorporated is a global leader in the animal health pharmaceutical industry, dedicated to improving the health and well-being of both pets and farm animals worldwide. Founded in 1954 as a division of Eli Lilly and Company, Elanco became an independent public company in 2018 and has since grown to become the world's second-largest independent animal health company. With approximately 9,000 employees globally, the company operates with a clear purpose: 'making life better for animals, makes life better.' Elanco develops innovative medicines, vaccines, and health solutions that empower veterinarians, farmers, and pet owners to advance animal care. The company maintains a balanced portfolio between pet health and farm animal products, offering over 200 brands that address critical health challenges ranging from companion animal diseases to livestock productivity. Headquartered in Indianapolis, Indiana, Elanco is publicly traded on the New York Stock Exchange (NYSE: ELAN) and continues to drive innovation in animal health through strategic acquisitions and dedicated research and development efforts.