Metagenome Research Scientist (ID: 107907)
Berkeley Lab
Summary
Berkeley Lab's Joint Genome Institute (JGI) has an opening for a Metagenome Research Scientist to join the Metagenome Program. In this role, you will lead large-scale analyses of multi-year, multi-site metagenomic and metatranscriptomic time-series datasets, including NEON and MONet, to characterize microbial community dynamics and infer spatiotemporal interactions across ecosystems.
Job description
What You Will Do
- Lead large-scale analyses of longitudinal metagenomic datasets (e.g., NEON and MONet) to investigate microbial community assembly, succession, stability, and interactions across environmental gradients.
- Develop scientific directions, lead programmatic initiatives, support JGI users, and contribute to Metagenome Program production activities.
- Formulate and test ecological hypotheses and develop innovative, theory-driven analytical frameworks to understand spatiotemporal microbial interactions.
- Design, benchmark, and implement scalable computational methods and workflows for analyzing longitudinal metagenomic and metatranscriptomic data.
- Collaborate with JGI data scientists and computational teams to leverage the Data Lakehouse, integrating time-series data, MAG abundance profiles, and environmental metadata into predictive models of microbial function.
- Provide scientific leadership for CSP and FICUS projects, collaborating with JGI users, DOE BER investigators, NEON, EMSL, and external partners.
- Partner with JGI production, project management, IMG, and GOLD teams to operationalize research methods into standardized, reusable tools for the broader user community.
- Lead scientific publications and present findings at conferences, consortium meetings, and JGI user meetings.
- Supervise and develop team members, including recruitment, work direction, performance management, and professional development.
- Mentor and train postdoctoral researchers and technical staff in longitudinal metagenomics, ecological statistics, and data synthesis.
- Represent the JGI in cross-institutional working groups and workshops focused on continental-scale ecology, time-series standards, and environmental microbiome dynamics.
What We Are Looking For
- A Ph.D. (or equivalent knowledge/training) in Bioinformatics, Computational Biology, Microbiology, Molecular Biology, Biochemistry or a related discipline and a minimum of 3 years of demonstrated expertise in Microbial Ecology or an equivalent combination of education and experience.
- Demonstrated experience analyzing complex metagenome, metatranscriptome, and genomic datasets, and longitudinal and time-series data analysis, assembly, binning and metagenome-assembled genome (MAG) generation, functional annotation, and taxonomic profiling.
- Demonstrated expertise in Microbial Ecology, including community assembly rules, niche differentiation, metabolic handoffs, spatiotemporal dynamics, and interaction network topology.
- Experience working in high-performance computing (HPC) environments to analyze large-scale biological datasets.
- Demonstrated proficiency with statistical programming and computational tools, such as Python, R, and UNIX/Linux environments, for advanced multivariate data analysis, time-series modeling, and visualization.
- Demonstrated ability to develop and scale reproducible computational workflows (e.g., WDL, Nextflow, and Snakemake) for large, multi-sample datasets.
- A strong record of impactful, peer-reviewed scientific publications demonstrating contributions to ecological hypothesis testing, microbiome analysis, or multi-omic data integration.
- Strong analytical skills, including the ability to develop creative solutions to complex problems, while addressing research needs in an effective and timely manner.
- Excellent organizational skills, including the ability to manage complex, multi-tiered projects with competing priorities, while meeting milestones.
- Demonstrated oral, written, and presentation skills including the ability to communicate complex ecological and computational concepts effectively with internal and external staff, JGI users, and scientific collaborators.
- Excellent interpersonal communication skills including collaborating effectively across interdisciplinary teams, bridging ecological domain science with computational engineers, data scientists, and external biological research.
Desired Qualifications
- A Ph.D. in Bioinformatics, Computational Biology, Microbiology, Molecular Biology, Biochemistry or a related discipline.
- Familiarity with continental-scale environmental monitoring programs (e.g., NEON, MONet) or longitudinal soil and aquatic microbiome datasets.
- Experience applying machine learning, network inference, dynamic systems modeling, or predictive modeling to investigate microbial interactions.
- Demonstrated ability to effectively supervise staff, including assigning work, providing coaching and performance feedback, and supporting employee development.
Requirements
- Ph.D. (or equivalent knowledge/training) in Bioinformatics, Computational Biology, Microbiology, Molecular Biology, Biochemistry or a related discipline
- Minimum of 3 years of demonstrated expertise in Microbial Ecology or an equivalent combination of education and experience
- Demonstrated experience analyzing complex metagenome, metatranscriptome, and genomic datasets, and longitudinal and time-series data analysis, assembly, binning and metagenome-assembled genome (MAG) generation, functional annotation, and taxonomic profiling
- Demonstrated expertise in Microbial Ecology, including community assembly rules, niche differentiation, metabolic handoffs, spatiotemporal dynamics, and interaction network topology
- Experience working in high-performance computing (HPC) environments to analyze large-scale biological datasets
- Demonstrated proficiency with statistical programming and computational tools, such as Python, R, and UNIX/Linux environments, for advanced multivariate data analysis, time-series modeling, and visualization
- Demonstrated ability to develop and scale reproducible computational workflows (e.g., WDL, Nextflow, and Snakemake) for large, multi-sample datasets
- A strong record of impactful, peer-reviewed scientific publications demonstrating contributions to ecological hypothesis testing, microbiome analysis, or multi-omic data integration
- Strong analytical skills, including the ability to develop creative solutions to complex problems, while addressing research needs in an effective and timely manner
- Excellent organizational skills, including the ability to manage complex, multi-tiered projects with competing priorities, while meeting milestones
- Demonstrated oral, written, and presentation skills including the ability to communicate complex ecological and computational concepts effectively with internal and external staff, JGI users, and scientific collaborators
- Excellent interpersonal communication skills including collaborating effectively across interdisciplinary teams, bridging ecological domain science with computational engineers, data scientists, and external biological research
Benefits
- Health Benefits
- Retirement Benefits
- Pension
- 401(k)-Style Plans
- Vacation Time
- Sick Time
- Winter Holiday Shutdown
- Parental Bonding Leave
- Pet Insurance
Company overview
Lawrence Berkeley National Laboratory (Berkeley Lab) is a premier federally funded research and development center established in 1931 and managed by the University of California for the U.S. Department of Energy. With a distinguished history spanning over 90 years, Berkeley Lab has been awarded 17 Nobel Prizes and operates as a multidisciplinary research institution focused on discovery science and energy solutions. The laboratory's expertise encompasses six major research areas: Computing Sciences, Physical Sciences, Earth and Environmental Sciences, Biosciences, Energy Sciences, and Energy Technologies. Berkeley Lab operates five national scientific user facilities including the Advanced Light Source, Joint Genome Institute, Molecular Foundry, National Energy Research Scientific Computing Center (NERSC), and Energy Sciences Network (ESnet), serving over 14,000 researchers annually. The institution is renowned for its team science approach, pioneering research in particle physics, materials science, genomics, and climate science, while maintaining a strong commitment to addressing global energy challenges and advancing fundamental scientific knowledge.