mRNA Associate Manufacturing Scientist I
GenScript/ProBio
Summary
Conduct DNA processing through PCR, digestion, and purification techniques to ready templates for in-vitro transcription.
Job description
Position Overview
Conduct DNA processing through PCR, digestion, and purification techniques to ready templates for in-vitro transcription.
Execute diverse enzymatic reactions as per Standard Operating Procedures (SOP) to generate and refine mRNA.
Employ High-Performance Liquid Chromatography (HPLC), spin columns, and LiCl precipitation for the purification of mRNA.
Adhere strictly to validated processes outlined in Standard Operating Procedures (SOPs) during the production phase.
Rigorously document all processes and materials employed for each product, ensuring compliance with ISO 9001 regulations.
Maintain inventory records through an advanced inventory management system.
Facilitate the procurement of materials for production through internal and external channels.
Undertake any additional tasks as assigned by the production manager to contribute to the seamless operation of the production process.
Qualifications
- Bachelor's degree in Biology or Chemistry related field
- Experience working with mRNA is a plus
- Experience with PCR, HPLC, or enzymatic reactions is desired
- Ability to work as part of a small cross-disciplinary team to accomplish both short term and long term goals
- Ability to quickly and accurately perform tasks in high repetition
- Experience successfully working in a fast-pace, high-demand environment is highly desirable
- Ability to communicate with peers and managers in a polite and concise manner is highly desirable
Requirements
- Bachelor's degree in Biology or Chemistry related field
- Experience working with mRNA is a plus
- Experience with PCR, HPLC, or enzymatic reactions is desired
- Ability to work as part of a small cross-disciplinary team
- Ability to quickly and accurately perform tasks in high repetition
- Experience working in a fast-paced, high-demand environment is highly desirable
- Ability to communicate with peers and managers politely and concisely
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Retirement Savings Plan
- Short-Term Disability
- Long-Term Disability
- Paid Parental Leave
- Paid Time Off
- Paid Company Holidays
- Paid Sick Leave
- Compassionate Leave
- Jury Duty Leave
- Floating Holidays
- Personal Days
- Free Meals During Shifts
- Flexible Spending Accounts
- Health Savings Accounts
- Life & AD&D Insurance
- Legal Assistance
- Supplemental Insurance
- Commuter Benefits
- Well-Being Initiatives
- Peer Recognition Programs
Company overview
GenScript ProBio is a global contract development and manufacturing organization (CDMO) specializing in advanced therapies, operating as a subsidiary of GenScript Biotech Corporation. Founded in 2020 and headquartered in Pennington, New Jersey, the company provides end-to-end CDMO services from drug discovery to commercialization, with a particular focus on cell and gene therapies, biologics, and recombinant protein drugs. ProBio's comprehensive service portfolio includes plasmid DNA manufacturing, viral vector production (AAV and lentiviral platforms), antibody discovery, mRNA vaccines, and antibody-drug conjugates. The company operates state-of-the-art GMP facilities, including a flagship 128,000 sq ft Cell and Gene Therapy Center of Excellence in Hopewell, New Jersey, which supports clinical-stage development and manufacturing. With expertise spanning CGT, antibody development, and protein therapeutics, ProBio aims to accelerate drug development timelines for biopharmaceutical innovators through proactive strategies, professional solutions, and efficient processes. The company has supported over 135 IND programs globally and employs advanced technologies to streamline therapeutic development from concept to clinic.