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NGS Scientist I

Tempus AI

Chicago, ILOnsitePosted 47 days ago$75,000 - $95,000/year
Full TimeMid LevelResearch & ScientistAI Biotech
Original posting ↗

Summary

We are seeking a Scientist to support the development, optimization and validation of molecular assays and laboratory processes for deployment in our high-throughput clinical laboratory.

Job description

What You'll Do

  • Perform hands-on assay development for advanced molecular and NGS-based workflows in a CAP/CLIA/NYSDOH regulated clinical laboratory
  • Design, execute, and analyze R&D experiments with strong attention to detail and scientific rigor
  • Design and execute qualification and validation studies for reagents, instruments, equipment, and methods to support clinical deployment.
  • Interpret data, troubleshoot issues, and drive process improvements.
  • Support automation and technology initiatives to improve laboratory workflows.
  • Maintain clear and comprehensive documentation of methods, materials, and results
  • Train and mentor junior scientific staff and support implementation of new laboratory workflows as needed
  • Collaborate across cross-functional teams and provide scientific support in a matrixed environment.
  • Communicate clearly and effectively with technical and non-technical stakeholders.
  • Manage multiple priorities and adapt quickly in a fast-paced environment.
  • Travel up to 10% as needed

Qualifications

  • Bachelor's degree with 5+ years, or Master's degree with 2+ years of relevant experience in molecular biology, assay development, or a related field.
  • Strong analytical, troubleshooting, and experimental design skills.
  • Ability to interpret results using scientific literature and SME input to refine experimental design
  • Highly organized, detail-oriented, and committed to quality and accuracy.
  • Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
  • Strong collaboration skills with the ability to lead across teams.
  • Excellent oral and written communication skills.
  • Experience working in dynamic environments with competing priorities and deadlines

Preferred Technical Experience

  • Hands-on experience with one or more of the following:
  • DNA/RNA extraction and purification methods.
  • PCR-based techniques, including PCR, qPCR, RT-PCR, and ddPCR.
  • Nucleic acid manipulation, quantitation, and analysis.
  • Assay troubleshooting, root cause analysis, and workflow optimization.

Highly Desirable

  • NGS library preparation, hybrid capture, and sequencing workflows.
  • Experience with laboratory automation and liquid handling robotics
  • Prior experience in a clinical laboratory environment
  • Familiarity with LIMS and laboratory data systems

Requirements

  • Bachelor's degree with 5+ years, or Master's degree with 2+ years of relevant experience in molecular biology, assay development, or a related field.
  • Strong analytical, troubleshooting, and experimental design skills.
  • Ability to interpret results using scientific literature and SME input to refine experimental design
  • Highly organized, detail-oriented, and committed to quality and accuracy.
  • Proven ability to learn quickly and adapt to new processes, technologies, and workflows.
  • Strong collaboration skills with the ability to lead across teams.
  • Excellent oral and written communication skills.
  • Experience working in dynamic environments with competing priorities and deadlines

Benefits

  • Medical benefits
  • Incentive compensation
  • Restricted stock units

Company overview

Tempus AI, Inc. (NASDAQ: TEM) is a pioneering healthcare technology company founded in 2015 by Eric Lefkofsky in Chicago, Illinois. The company was established after Lefkofsky's wife was diagnosed with breast cancer, driving his mission to revolutionize cancer care through technology and artificial intelligence. Tempus specializes in applying AI to advance precision medicine by collecting and analyzing vast amounts of molecular, clinical, and genomic data. The company operates across multiple therapeutic areas including oncology, cardiology, radiology, neurology, psychiatry, and dermatology. Tempus provides comprehensive diagnostic services including next-generation sequencing (NGS), PCR profiling, and molecular pathology testing. Its AI-powered platform enables physicians to make real-time, data-driven decisions for personalized patient care and targeted therapies. The company went public in June 2024 and has expanded globally with operations in multiple countries. Tempus continues to innovate at the intersection of healthcare and artificial intelligence, aiming to ensure patients receive the right treatments at the right time for improved health outcomes.

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