Postdoctoral Scientist: Functional Genome Engineering
Bayer
Summary
As a Postdoctoral Scientist in Functional Genome Engineering, you will join Bayer Crop Science R&D as a key contributor to functional genomics and high-throughput (HTP) screening initiatives. In this role, you bridge wet lab and computational biology approaches to identify novel targets and biological pathways in organisms of interest. Working closely with a multidisciplinary research team, you will serve as a technical expert responsible for establishing advanced functional genomics platforms, designing and executing HTP genetic perturbation screens, and generating insights that support decision-making, problem-solving, and pipeline innovation across the organization.
Job description
Your Tasks and Responsibilities
- Design and execute genetic perturbation screens in various organisms of interest and cell lines
- Establish and optimize gene perturbation tools and reagents for various applications
- Conduct in-depth data analyses and design controlled experiments in collaboration with cross-functional partners, coordinating their implementation to enable project success
- Understand and anticipate broader project and team interests, identifying, proposing, and performing complementary analyses to enrich insights from multiple modalities and data layers
- Conduct complex activities that require specialized knowledge and the broad application of scientific principles
- Take initiative in keeping current with literature in areas of assignment and professional interest
- Maintain detailed record-keeping and required documentation
- Demonstrate commitment to inclusion and safety, adhering to safety protocols and best practices
Required Qualifications
- Ph.D. in a biological or biomedical field, molecular or cell biology, genetics or genomics, bioinformatics, or a similar area
- Proven experience with CRISPR screens or related gene perturbation technologies using pooled or targeted approaches
- Experience with next-generation transcriptomics analysis or a related area
- Experience working in an AWS cloud computing environment and proficiency in at least one programming language (Python, R, etc.)
- Familiarity with innovative or emerging fields of study
- Strong problem-solving skills with a commitment to high-quality deliverables and the ability to build productive internal and external relationships
Preferred Qualifications
- Experience with library preparation for high-throughput pooled or targeted approaches screening techniques
- Knowledge of machine learning applications for functional genomics
- Experience with agricultural specimens
- Experience collaborating across multiple teams, fostering a team-based approach to research, and leveraging partnerships
- Experience clearly communicating project plans and experimental results with partners and stakeholders, maintaining alignment on objectives and priorities
Requirements
- Ph.D. in a biological or biomedical field, molecular or cell biology, genetics or genomics, bioinformatics, or a similar area
- Proven experience with CRISPR screens or related gene perturbation technologies using pooled or targeted approaches
- Experience with next-generation transcriptomics analysis or a related area
- Experience working in an AWS cloud computing environment and proficiency in at least one programming language (Python, R, etc.)
- Familiarity with innovative or emerging fields of study
- Strong problem-solving skills with a commitment to high-quality deliverables and the ability to build productive internal and external relationships
- Experience with library preparation for high-throughput pooled or targeted approaches screening techniques
- Knowledge of machine learning applications for functional genomics
- Experience with agricultural specimens
- Experience collaborating across multiple teams, fostering a team-based approach to research, and leveraging partnerships
- Experience clearly communicating project plans and experimental results with partners and stakeholders, maintaining alignment on objectives and priorities
Benefits
- Health care
- Vision
- Dental
- Retirement
- PTO
- Sick leave
Company overview
Bayer AG is a global life science company with core competencies in healthcare and agriculture, operating as one of the world's leading pharmaceutical corporations. Founded in 1863 and headquartered in Leverkusen, Germany, Bayer operates through three primary divisions: Pharmaceuticals, Consumer Health, and Crop Science. The company's pharmaceutical segment focuses on prescription products for cardiology, women's healthcare, oncology, hematology, and ophthalmology, with blockbuster drugs including Xarelto, Eylea, and Nubeqa. Bayer's Consumer Health division markets well-known over-the-counter brands such as Aspirin, Aleve, Claritin, and Bepanthen. The Crop Science division, strengthened by the acquisition of Monsanto, provides seeds, crop protection products, and digital farming solutions. With approximately 92,815 employees worldwide and operations in 80 countries, Bayer is committed to its mission of "Health for all, Hunger for none," driving innovation in medical treatments, agricultural productivity, and sustainable development. The company maintains a strong research and development pipeline, investing heavily in areas like precision medicine, artificial intelligence applications in healthcare, and sustainable agricultural technologies.