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Principal Business Manager, Early Clinical Development (ECD)

Roche

South San Francisco, CAHybridPosted 31 days ago$136,100 - $252,700/year
Full TimeSenior LevelProgram / Project ManagementPharmaceutical
Original posting ↗

Summary

The Early Clinical Development (ECD) Business Manager acts as a key strategic advisor to the assigned Leadership Team and Senior Leaders within gRED ECD. Reporting directly to the ECD Chief of Staff, this role leads short- and long-term business planning, strategy formulation, resource allocation, budget oversight, and execution across the department.

Job description

The Opportunity

  • Cross-Functional Collaboration: Fosters team alignment and builds networks across functions, enterprise teams, and external partners to achieve key milestones.
  • Talent & Team Engagement: Drives talent development, engagement programs, departmental workshops, and recognition initiatives to foster professional growth.
  • Strategic Leadership Partnership: Serves as a thought partner to executive leadership, advising on priorities, providing constructive challenge, and driving short- and long-term enterprise strategy.
  • Meeting Facilitation & Action Tracking: Structures leadership meetings with clear agendas, concise documentation, and rigorous follow-up on action items.
  • Business & Financial Planning: Oversees annual planning, resource forecasting, budget allocation, and goal setting.
  • Operational Strategy & Innovation: Balances innovation with guardrails, recommending operational strategies to address evolving enterprise needs.
  • Complex Problem Solving: Resolves complex business challenges by mobilizing stakeholders and aligning functional goals with broader organizational priorities.
  • Working Hours: Ability to work over 8 hours/day or 40 hours/week, including early morning or late-night calls, to meet business demands.
  • Rapid Responsiveness: Capacity to respond promptly to emails and phone calls as business needs arise.
  • Physical Capability: Ability sitting or standing for extended periods during back-to-back meetings.
  • Onsite Mobility: Ability to carry up to 10 lbs of materials and travel between campus buildings for meetings and offsites.
  • Travel: Ability to travel domestically and internationally as needed.

Who You Are

  • Education & Certifications: Bachelor's degree required; project management or process improvement certifications (PMP, Six Sigma, Agile, Change Management) preferred.
  • Experience: 5–10 years in business management, cross-functional initiatives, or operations programs (clinical development experience preferred).
  • Core Competencies: Expertise in strategic planning, project management, business process improvement, and team facilitation.
  • Problem Solving & Innovation: Proactive problem solver skilled at challenging standard processes, proposing creative solutions, and adapting to fast-changing demands.
  • Communication & Relationships: Strong written, oral, and presentation skills with a proven ability to build transparent, productive cross-functional relationships.
  • Change Leadership: Demonstrated ability to develop and execute change management and communication strategies across the enterprise.

Requirements

  • Bachelor's degree required
  • 5–10 years in business management, cross-functional initiatives, or operations programs
  • Expertise in strategic planning
  • Expertise in project management
  • Expertise in business process improvement
  • Expertise in team facilitation
  • Proactive problem solver skilled at challenging standard processes
  • Strong written, oral, and presentation skills
  • Proven ability to build transparent, productive cross-functional relationships
  • Demonstrated ability to develop and execute change management and communication strategies

Benefits

  • Annual bonus
  • Medical, Dental & Vision
  • 401(k) Matching
  • Paid Time Off

Company overview

Roche is a Swiss multinational healthcare company and a global pioneer in pharmaceuticals and diagnostics, founded in 1896 and headquartered in Basel, Switzerland. As the world's largest biotech company and the fifth-largest pharmaceutical company by revenue, Roche operates through two primary divisions: Pharmaceuticals and Diagnostics. The company is renowned for its leadership in personalized healthcare, combining strengths in both drug development and diagnostic testing to deliver tailored treatments for patients. Roche maintains a strong focus on oncology, immunology, infectious diseases, ophthalmology, and central nervous system disorders, with a portfolio that includes over 30 medicines on the World Health Organization's Model Lists of Essential Medicines. The company owns significant subsidiaries including Genentech, Chugai Pharmaceuticals, Ventana Medical Systems, and Foundation Medicine. With approximately 103,000 employees worldwide and operations in over 100 countries, Roche has established itself as a leader in cancer treatments globally while maintaining a robust pipeline of innovative therapies and diagnostic solutions. The company's commitment to sustainability has been recognized through ten consecutive years as Group Leader in the Dow Jones Sustainability Indices within the Pharmaceuticals, Biotechnology & Life Sciences Industry.

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