Principal Investigator (MD/DO)
ALLIANCE CLINICAL LLC
Summary
This is more than an opportunity to serve as a Principal Investigator. It's an opportunity to help build a new clinical research site from the ground up. As the Principal Investigator, you'll provide clinical and medical guidance as the site establishes itself in the community and grows its research portfolio.
Job description
The Opportunity
This is more than an opportunity to serve as a Principal Investigator. It's an opportunity to help build a new clinical research site from the ground up. As the Principal Investigator, you'll provide clinical and medical guidance as the site establishes itself in the community and grows its research portfolio.
What You'll Do
As Principal Investigator, you will provide medical oversight and clinical leadership for assigned clinical trials, with patient safety and data quality at the center of your work.
- Serve as the study physician and provide medical oversight for assigned clinical trials.
- Protect the safety, rights, and well-being of research participants throughout the study.
- Review and confirm participant eligibility and provide medical oversight of screening outcomes.
- Review adverse events (AEs), serious adverse events (SAEs), and participant safety trends.
- Perform or oversee study-specific medical assessments, including medical histories, physical examinations, concomitant medications, and endpoint assessments.
- Provide clinical guidance and medical oversight to Sub-Investigators, Clinical Research Coordinators, RNs, and other site staff.
- Serve as a clinical resource for study-related medical questions and safety concerns.
- Collaborate with study sponsors, CROs, IRBs, and Alliance leadership throughout the life of each trial.
- Participate in Site Initiation Visits, monitoring visits, close-out activities, and other study meetings as needed.
- Review clinical data including laboratory results, ECGs, vital signs, and other study-specific assessments.
- Support timely safety reporting, medical documentation, and resolution of clinical data queries.
- Maintain compliance with study protocols, site SOPs, ICH-GCP, FDA regulations, and applicable Florida requirements.
- Contribute to a culture of quality, continuous improvement, and patient-centered research.
A Schedule Designed Around Your Life
- Opportunity to transition into the role from your current work; starting at approximately 10 hours per week and moving to full-time
- No overnight call & rare urgent escalations
- Predictable research visits and structured protocols
- Focused interactions with study participants rather than a traditional high-volume clinic
- A dedicated research team managing day-to-day study coordination
Training & Support
- Structured PI onboarding and mentorship
- Protocol-specific training
- Support from other experienced Principal Investigators
- Ongoing partnership with clinical operations, regulatory, and quality teams
- Established SOPs, templates, and documentation workflows
- Continued support throughout the life of your studies
What We're Looking For
- MD or DO with a background in Internal Medicine, Family Medicine or a Specialist
- Active, unrestricted Pennsylvania medical license
- Prior clinical research experience in a Principal Investigator, Sub-Investigator, or other clinical research physician capacity is required
- Strong clinical judgment and commitment to participant safety
- Interest in clinical research and advancing medical innovation
- Comfort reviewing structured clinical data and study-specific medical information
- Strong communication, documentation, and confidentiality practices
- Familiarity with ICH-GCP and FDA clinical research regulations
- Board certification
- DEA registration, if required by applicable study protocols
Requirements
- MD or DO with a background in Internal Medicine, Family Medicine or a Specialist
- Active, unrestricted Pennsylvania medical license
- Prior clinical research experience in a Principal Investigator, Sub-Investigator, or other clinical research physician capacity is required
- Strong clinical judgment and commitment to participant safety
- Interest in clinical research and advancing medical innovation
- Comfort reviewing structured clinical data and study-specific medical information
- Strong communication, documentation, and confidentiality practices
- Familiarity with ICH-GCP and FDA clinical research regulations
- Board certification
- DEA registration, if required by applicable study protocols
Benefits
- Structured PI onboarding
- Mentorship
- Protocol-specific training
- Support from experienced Principal Investigators
- Predictable schedule
Company overview
ALLIANCE CLINICAL LLC is a clinical research organization that specializes in managing medical practices and conducting clinical trials. The company operates at the intersection of healthcare delivery and clinical research, providing comprehensive services to support medical professionals and research initiatives. As a limited liability company, ALLIANCE CLINICAL focuses on creating collaborative networks between healthcare providers, researchers, and pharmaceutical companies to facilitate efficient clinical trial execution. The organization likely offers services including patient recruitment, clinical site management, regulatory compliance support, and data collection for medical research studies. By bridging the gap between clinical practice and research, ALLIANCE CLINICAL LLC plays a crucial role in advancing medical knowledge and improving patient care through evidence-based medicine. Their work contributes to the development of new treatments and therapies while maintaining high standards of patient safety and ethical research practices.