Principal Investigator, MD/DO

The Opportunity

We are seeking a Principal Investigator (MD/DO) to join our clinical research team in Scottsdale, Arizona. This is an exciting opportunity for a physician who is passionate about patient care, medical innovation, and advancing new treatments through clinical research. As a Principal Investigator, you will provide medical leadership and oversight for clinical trials, ensuring participant safety, regulatory compliance, and high-quality study execution. Prior clinical research experience is preferred but not required.

Key Responsibilities

• Serve as Principal Investigator for assigned clinical trials, providing medical oversight and ensuring studies are conducted in accordance with approved protocols, Good Clinical Practice (GCP), and applicable regulatory requirements.
• Maintain responsibility for participant safety, medical decision-making, and the overall quality and integrity of clinical trial conduct.
• Evaluate potential study participants for eligibility, review medical histories, and assess clinical findings.
• Oversee the informed consent process, ensuring participants understand study procedures, potential risks, and their rights.
• Evaluate, document, and oversee the reporting of adverse events and serious adverse events in accordance with study protocols and regulatory requirements.
• Provide medical oversight for investigational products, including appropriate administration, monitoring, and assessment of treatment responses.
• Collaborate with clinical research coordinators, Sub-Investigators, and other site personnel to ensure efficient and compliant study execution.
• Ensure appropriate delegation of study responsibilities to qualified research personnel and provide ongoing supervision and training.
• Review and maintain accurate, complete, and timely clinical research documentation.
• Participate in sponsor meetings, investigator meetings, site initiation visits, monitoring visits, and regulatory inspections as needed.
• Work collaboratively with sponsors, Contract Research Organizations (CROs), Institutional Review Boards (IRBs), and regulatory agencies.
• Support participant recruitment and retention efforts while maintaining the highest standards of ethical research conduct.

Required Qualifications

• Doctor of Medicine (MD) or Doctor of Osteopathic Medicine (DO) degree from an accredited institution.
• Active, unrestricted medical license in the state of Arizona, or eligibility to obtain an Arizona medical license prior to beginning clinical research responsibilities.
• Board-certified or board-eligible in a recognized medical specialty.
• Strong clinical judgment and commitment to patient safety and ethical medical practices.
• Excellent interpersonal, communication, and organizational skills.
• Ability to work collaboratively with multidisciplinary clinical research teams.
• Willingness to learn and follow clinical trial protocols, GCP guidelines, and applicable regulatory requirements.

Preferred Qualifications

• Previous experience serving as a Principal Investigator or Sub-Investigator in clinical research.
• Familiarity with FDA regulations, ICH-GCP guidelines, and clinical trial documentation requirements.
• Experience working with pharmaceutical sponsors, CROs, or clinical research organizations.
• Experience evaluating and managing patients in therapeutic areas relevant to the site's clinical trial portfolio.
• Demonstrated ability to provide medical leadership and collaborate effectively with clinical and operational teams.