Principal Scientist, Surface Chemistry
Roche
Summary
We are seeking a talented scientist to join a team developing surface chemistries enabling NGS-based advanced applications and consumables. This position provides an exciting opportunity to work with outstanding scientists and engineers in a highly multidisciplinary environment. The successful candidate will have a broad background in surface science and device development.
Job description
The Position
We are seeking a talented scientist to join a team developing surface chemistries enabling NGS-based advanced applications and consumables. This position provides an exciting opportunity to work with outstanding scientists and engineers in a highly multidisciplinary environment. The successful candidate will have a broad background in surface science and device development.
The Opportunity
- You will design and develop surface modifications and novel chemistries and workflows enabling consumables for NGS applications.
- You will develop assays and methods to characterize surface modifications and surface-biomolecule interactions in complex consumable devices.
- You will drive the synthetic manipulation of material surfaces at a molecular level to precisely engineer surface energy characteristics and other properties that will ensure optimal device performance in a complex system.
- You will use early stage instrumentation and SW and gain a deep understanding of the sequencing workflow and consumables.
- You will design and execute studies to determine optimal process conditions for surface modifications, including sequencing data collection and data analysis.
- You will support design and process transfer from R&D to Ops.
- You will analyze complex data sets, author technical reports, and present findings and strategic recommendations to the team and the organization.
Who You Are
- You have a BS degree with 7+ years of industrial experience, MS with 4+ years of industrial experience, or PhD degree with 3+ years of industrial experience in Chemistry or a closely related field, with a focus on surface science and materials modification and development of surface modifications for biomolecule analysis.
- Deep understanding of chemical principles governing interactions at biomolecule-device interfaces.
- Proficiency in JMP and Python to interpret complex datasets and translate findings into actionable insights
Behaviors, competencies, and qualities of the ideal applicant.
- You have experience with NGS-based applications and/or platform development, including an understanding of the critical surface requirements
- Understanding of principles and challenges of surface functionalization of microfluidic and lab-on-chip complex consumables.
- Problem-solving and data-driven solutions, with aptitude for systematically analyzing issues within multidisciplinary systems
- Experience with early stage instrumentation
Requirements
- BS degree with 7+ years of industrial experience, MS with 4+ years, or PhD with 3+ years in Chemistry or a closely related field
- Focus on surface science and materials modification and development of surface modifications for biomolecule analysis
- Deep understanding of chemical principles governing interactions at biomolecule-device interfaces
- Proficiency in JMP and Python to interpret complex datasets and translate findings into actionable insights
- Experience with NGS-based applications and/or platform development, including an understanding of the critical surface requirements
- Understanding of principles and challenges of surface functionalization of microfluidic and lab-on-chip complex consumables
- Problem-solving and data-driven solutions, with aptitude for systematically analyzing issues within multidisciplinary systems
- Experience with early stage instrumentation
Benefits
- Annual bonus
- Medical, Dental & Vision
- 401(k) Matching
- Paid Time Off
Company overview
Roche is a Swiss multinational healthcare company and a global pioneer in pharmaceuticals and diagnostics, founded in 1896 and headquartered in Basel, Switzerland. As the world's largest biotech company and the fifth-largest pharmaceutical company by revenue, Roche operates through two primary divisions: Pharmaceuticals and Diagnostics. The company is renowned for its leadership in personalized healthcare, combining strengths in both drug development and diagnostic testing to deliver tailored treatments for patients. Roche maintains a strong focus on oncology, immunology, infectious diseases, ophthalmology, and central nervous system disorders, with a portfolio that includes over 30 medicines on the World Health Organization's Model Lists of Essential Medicines. The company owns significant subsidiaries including Genentech, Chugai Pharmaceuticals, Ventana Medical Systems, and Foundation Medicine. With approximately 103,000 employees worldwide and operations in over 100 countries, Roche has established itself as a leader in cancer treatments globally while maintaining a robust pipeline of innovative therapies and diagnostic solutions. The company's commitment to sustainability has been recognized through ten consecutive years as Group Leader in the Dow Jones Sustainability Indices within the Pharmaceuticals, Biotechnology & Life Sciences Industry.