Process Development Engineer III, Novel Molecule Purification Development (PMPD)
Regeneron Pharmaceuticals
Summary
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer III to join our Preclinical Manufacturing & Process Development Group (PMPD), working in the Purification Development group. In this role, you will be responsible for the purification of various pre-clinical biological molecules to provide reagents for Regeneron's research and discovery groups. This is a lab-based role that requires real-time data interpretation, problem-solving, and innovation.
Job description
Build our future together
At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Process Development Engineer III to join our Preclinical Manufacturing & Process Development Group (PMPD), working in the Purification Development group. In this role, you will be responsible for the purification of various pre-clinical biological molecules to provide reagents for Regeneron's research and discovery groups. This is a lab-based role that requires real-time data interpretation, problem-solving, and innovation.
When & where
- Shift Requirements: Full-time
- Location: On-site in Tarrytown, NY
- Other requirements: Job will periodically require short duration physical exertions, including light-medium weight lifting
Discover your role
- Purify a diverse array of proteins to support any of Regeneron's research and discovery groups, following established procedures when available, but recognizing unexpected results or improvement opportunities and modifying strategies appropriately
- Independently develop technology and automation to increase process throughput and efficiency of preclinical manufacturing
- Document experiments, results, and findings in an electronic laboratory notebook; present work to supervisor, subteam, group, department, and cross-functional meetings
- Maintain instruments and troubleshoot instrumental/experimental problems
- Collaborate with peers to complete core deliverables while exhibiting independence in planning, experimental execution with appropriate controls, data interpretation, and decision-making
- Ask pointed questions to eliminate ambiguity and provide appropriate solutions
- Apply creative problem-solving using novel incorporation of internal and external (literature) learnings
- Take calculated risks to achieve goals, independently and accurately determining strategies to address gaps and implement them effectively
- Communicate with all levels of the organization
- Coach, mentor, and support performance planning with other members of the organization as needed
- Represent PMPD in cross-functional collaborations and provide updates to PMPD Senior Staff as a departmental program team representative
- Enjoy a fast-paced pilot scale laboratory setting where sound science and teamwork are priorities
- Contribute to lab safety and equipment maintenance to help create a safe, effective, and efficient working environment
- Anticipate and recognize potential problems and act to prevent and tackle them
- Ensure training and/or compliance responsibilities are maintained
- Be scientifically curious, enthusiastic, and proactively ask questions to learn or seek clarification
- Communicate the high-level and detailed scientific story accurately depending on audience and need
- Bring an interest in a non-positional leadership role within a collaborative team
This role requires
- Degree in Chemical Engineering, Biochemical Engineering, or Biochemistry, with 0-2+ years of experience (Ph.D.), 3-5+ years (MS), or 7-10+ years (BS) of industrial experience
- Demonstrated ability to communicate complex messages clearly and credibly with multifaceted audiences, establishing multi-functional relationships that support proactive teamwork across the organization
- Strong fundamental understanding of various protein purification techniques is a plus
- Experience with downstream process development and with equipment like Akta Explorers/Avants/Pilots, chromatography columns, tangential flow filters, depth filters, HPLCs, and UPLCs, as well as software such as Empower, Unicorn, JMP, and Benchling, is a plus
Requirements
- Degree in Chemical Engineering, Biochemical Engineering, or Biochemistry
- 0-2+ years of experience (Ph.D.), 3-5+ years (MS), or 7-10+ years (BS) of industrial experience
- Demonstrated ability to communicate complex messages clearly and credibly with multifaceted audiences
- Establishing multi-functional relationships that support proactive teamwork across the organization
- Strong fundamental understanding of various protein purification techniques is a plus
- Experience with downstream process development is a plus
- Experience with Akta Explorers/Avants/Pilots, chromatography columns, tangential flow filters, depth filters, HPLCs, and UPLCs is a plus
- Experience with software such as Empower, Unicorn, JMP, and Benchling is a plus
Benefits
- Annual bonuses
- Incentive plans
- Equity awards
- Pension or retirement benefits
- 401(k) company match
- Health and wellness programs
- Fitness centers
- Insurance benefits
- Paid time off
- Family support benefits
Company overview
Regeneron Pharmaceuticals is a leading American biotechnology company founded in 1988 and headquartered in Tarrytown, New York. The company specializes in inventing, developing, and commercializing life-transforming medicines for people with serious diseases. Regeneron is renowned for its innovative antibody technologies and has developed several groundbreaking therapies, including EYLEA® for retinal diseases, DUPIXENT® for inflammatory conditions, and the COVID-19 antibody cocktail REGEN-COV®. The company operates with a strong focus on research and development across multiple therapeutic areas including ophthalmology, oncology, cardiovascular diseases, and rare genetic disorders. Regeneron's proprietary VelocImmune® technology platform enables the rapid generation of fully human monoclonal antibodies. With over 15,000 employees globally and annual revenues exceeding $14 billion, Regeneron has established itself as a major force in the biotechnology industry, consistently ranking among the top-performing pharmaceutical companies and maintaining a robust pipeline of investigational therapies.