Process Development Senior Scientist
Amgen
Summary
In this vital role you will be responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.
Job description
What you will do
In this vital role you will be responsible for the invention, development, and implementation of drug substance manufacturing processes and technologies to advance Amgen's exciting portfolio of synthetic and hybrid assets. Process chemists within our team apply their synthetic training to invent synthetic routes and chemical processes to support drug substance manufacturing from early to late-stage development.
- Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances
- Advance enabling technologies to accelerate pharmaceutical development and to improve sustainability and process efficiency
- Support cGMP manufacturing and technology transfer to our internal manufacturing facilities and external contract manufacturers
- Ensure process performance through process understanding, modeling and characterization
- Contribute to drug substance development teams by providing experimental results, technical updates, documentation, data interpretation, recommendations, etc.
- Work cross-functionally to deliver regulatory documents and support regulatory filings
- Serve as a technical expert and keep current in the field of organic and process chemistry
- Work effectively in a multi-disciplinary team of chemists, engineers and attribute scientists
- Work independently in advancing projects and studies within required deadlines
What we expect of you
We are all different, yet we all use our unique contributions to serve patients. The professional we seek is highly motivated with these qualifications.
Basic Qualifications:
Doctorate degree PhD OR PharmD OR MD OR Master's degree and 3 years of industry experience OR Bachelor's degree and 5 years of industry experience
Preferred Qualifications:
- Ph.D. in organic chemistry and/or biochemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, and/or conjugation chemistry
- Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
- Track record of peer-reviewed publications and research presentations
- Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
- Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
- A research summary included with CV is strongly encouraged
Requirements
- Doctorate degree PhD OR PharmD OR MD OR Master's degree and 3 years of industry experience OR Bachelor's degree and 5 years of industry experience
- Ph.D. in organic chemistry and/or biochemistry with a specialization in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, and/or conjugation chemistry
- Post-doctoral experience in an academic laboratory or pharmaceutical/biotech industry
- Track record of peer-reviewed publications and research presentations
- Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results
- Excellent written and verbal communication skills, ability to multitask, effectively plan and follow through on complex projects
- A research summary included with CV is strongly encouraged
Benefits
- Health insurance
- Dental coverage
- Vision coverage
- Life insurance
- Disability insurance
- Retirement and savings plan
- Flexible spending accounts
- Annual bonus program
- Stock-based long-term incentives
- Paid time off
Company overview
Amgen Inc. is a leading American multinational biopharmaceutical company headquartered in Thousand Oaks, California, founded in 1980. As one of the world's largest independent biotechnology companies, Amgen specializes in discovering, developing, manufacturing, and delivering innovative human therapeutics. The company focuses on six key therapeutic areas: inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience. Amgen's portfolio includes blockbuster drugs such as Enbrel for autoimmune diseases, Prolia and XGEVA for osteoporosis, Repatha for cholesterol management, Otezla for psoriasis, and Neulasta for chemotherapy-induced neutropenia. With approximately 28,000 employees worldwide, Amgen operates as a component of both the Dow Jones Industrial Average and Nasdaq-100 indices. The company maintains a robust research and development pipeline with numerous clinical programs across various stages, leveraging cutting-edge biotechnology and human genetic data to address some of the world's most challenging diseases. Amgen's manufacturing capabilities span multiple global locations, and it distributes products through pharmaceutical wholesale distributors and direct-to-consumer channels.