Process Development Sr Associate
Amgen
Summary
Amgen is seeking a Process Development Senior Associate to join the Pivotal Drug Substance Technologies (DST) organization. The Pivotal DST organization is responsible for developing cell culture and purification manufacturing processes for Amgen's late-stage pipeline.
Job description
What you will do
Amgen is seeking a Process Development Senior Associate to join the Pivotal Drug Substance Technologies (DST) organization. The Pivotal DST organization is responsible for developing cell culture and purification manufacturing processes for Amgen's late-stage pipeline.
Scope of work includes developing cell culture and purification processes for recombinant proteins to improve the production yields, evaluating process robustness through process characterization, transferring processes to manufacturing, and conducting other relevant experiments such as facility fit and raw material evaluation.
- Work in a team environment to contribute to drug substance process development.
- Execute mammalian cell culture experiments at different scales in shake flasks and bioreactors.
- Execute purification experiments, mainly filtration and chromatography, at bench and pilot scale as needed.
- Document experimental data in lab notebooks.
- Analyze the data and present to the team.
- Author technical reports and support regulatory filing as needed.
- Contribute to technology development projects to seek continuous improvement in reliability and efficiency.
The candidate will have opportunities to work in cell culture development and purification development to become a well-rounded process development scientist with experience in upstream and downstream.
What we expect of you
Basic Qualifications
Master's degree OR Bachelor's degree and 2 years of experience OR Associate's degree and 4 years of experience OR High school diploma / GED and 6 years experience
Preferred Qualifications
- Relevant hands-on lab experience in cell culture or protein purification.
- Attention to details and critical thinking ability.
- Experience in Design of Experiments and statistical analysis is a plus.
- Strong oral and written communication skills.
- Self-motivated and strong organization skills.
- Strong interpersonal skills, and the ability to work in a dynamic and collaborative environment.
Requirements
- Master's degree OR Bachelor's degree and 2 years of experience OR Associate's degree and 4 years of experience OR High school diploma / GED and 6 years experience
- Relevant hands-on lab experience in cell culture or protein purification
- Attention to details and critical thinking ability
- Experience in Design of Experiments and statistical analysis is a plus
- Strong oral and written communication skills
- Self-motivated and strong organization skills
- Strong interpersonal skills, and the ability to work in a dynamic and collaborative environment
Benefits
- Health Insurance
- Dental Coverage
- Vision Coverage
- Life Insurance
- Disability Insurance
- Retirement and Savings Plan
- Flexible Spending Accounts
- Annual Bonus Program
- Stock-Based Long-Term Incentives
- Paid Time Off
Company overview
Amgen Inc. is a leading American multinational biopharmaceutical company headquartered in Thousand Oaks, California, founded in 1980. As one of the world's largest independent biotechnology companies, Amgen specializes in discovering, developing, manufacturing, and delivering innovative human therapeutics. The company focuses on six key therapeutic areas: inflammation, oncology/hematology, bone health, cardiovascular disease, nephrology, and neuroscience. Amgen's portfolio includes blockbuster drugs such as Enbrel for autoimmune diseases, Prolia and XGEVA for osteoporosis, Repatha for cholesterol management, Otezla for psoriasis, and Neulasta for chemotherapy-induced neutropenia. With approximately 28,000 employees worldwide, Amgen operates as a component of both the Dow Jones Industrial Average and Nasdaq-100 indices. The company maintains a robust research and development pipeline with numerous clinical programs across various stages, leveraging cutting-edge biotechnology and human genetic data to address some of the world's most challenging diseases. Amgen's manufacturing capabilities span multiple global locations, and it distributes products through pharmaceutical wholesale distributors and direct-to-consumer channels.