Process Engineer
Neurona Therapeutics
Summary
Neurona Therapeutics is a clinical stage biotechnology company based in South San Francisco focused on the development of neuronal cell-based therapies for intractable neurological diseases. The successful candidate will work as a member of the Process Sciences department and will be responsible for projects requiring design and qualification of process equipment, interfacing with Manufacturing, Process Science, Facilities, Validation, QA, and Contract Engineering/vendor firms.
Job description
Responsibilities
- Plan and execute small-scale process development experiments and develop viable cGMP manufacturing processes for cell culture and cryopreservation.
- May be required to participate in technology transfer activities.
- Contribute toward the development, optimization, and characterization of processes to manufacture and process human neural cell therapeutics.
- Assist with maintaining laboratories (equipment maintenance, calibration, cleaning and related documentation).
- Present data at departmental meetings.
- Must possess the ability to work independently or as a team.
- Maintain notebooks and electronic files associated with each experiment and contribute to the preparation of final experimental reports.
- Manage product and material inventories as needed throughout studies.
- Travel to clinical sites will be required (up to 40% of time).
Required Qualifications
- Bachelor's or master's degree in chemistry, biology or biochemistry.
- 2-6 years of laboratory research experience.
- Experience in aseptic handling of cell cultures with preference for stem cell culture maintenance and differentiation.
- Availability to work a limited number of hours on occasional weekends.
- Excellent writing, verbal communication, presentation, and interpersonal skills.
- Able to take initiative to improve work processes, develop innovative scientific methodologies and approaches to enhance process productivity.
Preferred Qualifications
- 2-5 years of industrial research experience.
- Previous experience with upstream or downstream cell culture process development.
- Previous experience with Immunocytochemistry and (confocal or fluorescent) microscopic image analysis is a plus.
- Knowledge of Good Laboratory Practices and current Good Manufacturing Practices is a plus.
Requirements
- Bachelor's or master's degree in chemistry, biology or biochemistry
- 2-6 years of laboratory research experience
- Experience in aseptic handling of cell cultures
- Availability to work occasional weekends
- Excellent writing, verbal communication, presentation, and interpersonal skills
- Ability to work independently or as a team
- 2-5 years of industrial research experience (preferred)
- Experience with upstream or downstream cell culture process development (preferred)
- Experience with Immunocytochemistry and microscopic image analysis (preferred)
- Knowledge of Good Laboratory Practices and cGMP (preferred)
Company overview
Neurona Therapeutics is a clinical-stage biotechnology company pioneering regenerative cell therapies for neurological disorders. The company specializes in developing allogeneic, off-the-shelf cell therapies derived from human pluripotent stem cells to treat chronic neurological conditions. Neurona's lead program focuses on NRTX-1001, an investigational cell therapy for drug-resistant focal epilepsy, which has shown promising results in early clinical trials. The company's proprietary platform enables the production of specific types of inhibitory interneurons that can restore neural circuit balance in the brain. Founded by leading neuroscientists, Neurona combines deep expertise in stem cell biology, neuroscience, and clinical development to address unmet medical needs in epilepsy, Alzheimer's disease, and other neurological disorders. The company's innovative approach represents a paradigm shift in treating chronic neurological conditions through regenerative medicine rather than symptom management alone.