Protein Purification Associate Scientist
GenScript/ProBio
Summary
We are seeking a skilled and detail-oriented Protein Purification Associate Scientist to join our US Protein Department. This role involves executing downstream processing activities including protein purification, characterization, and documentation. The ideal candidate will have a solid background in biochemistry, biotechnology, or a related field, along with hands-on experience in protein purification techniques in a laboratory or manufacturing setting.
Job description
Job Summary
We are seeking a skilled and detail-oriented Protein Purification Associate Scientist to join our US Protein Department. This role involves executing downstream processing activities including protein purification, characterization, and documentation. The ideal candidate will have a solid background in biochemistry, biotechnology, or a related field, along with hands-on experience in protein purification techniques in a laboratory or manufacturing setting.
Key Responsibilities
- Perform protein purification using a variety of chromatography techniques such as affinity, ion exchange, size exclusion, and hydrophobic interaction.
- Prepare buffers and reagents following SOPs and project-specific protocols.
- Characterize protein products using SDS-PAGE, Western Blot, HPLC, UV spectroscopy, BCA assay, and other analytical methods.
- Maintain accurate, complete, and timely documentation of experimental procedures and results.
- Troubleshoot and optimize purification protocols as needed to improve yield and purity.
- Collaborate closely with upstream, analytical, and quality teams to ensure project timelines and specifications are met.
- Assist in the revision and creation of SOPs, batch records, and technical reports.
- Support additional tasks and projects as assigned by the department supervisor.
Qualifications
- BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 1+ years of relevant experience in protein purification/characterization.
- Familiarity with AKTA systems and chromatography software is a strong plus.
- Strong organizational and documentation skills, with attention to detail and data integrity.
- Ability to work independently and as part of a team in a fast-paced environment.
- Excellent problem-solving and communication skills.
- Experience in a CRO or CDMO setting is preferred.
Requirements
- BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field
- 1+ years of relevant experience in protein purification/characterization
- Familiarity with AKTA systems and chromatography software is a strong plus
- Strong organizational and documentation skills
- Attention to detail and data integrity
- Ability to work independently and as part of a team
- Excellent problem-solving and communication skills
- Experience in a CRO or CDMO setting is preferred
Benefits
- Medical, Dental & Vision
- 401(k) Matching
- Paid Parental Leave
- Paid Time Off
- Flexible Spending Account
- Health Savings Account
- Life & AD&D Insurance
- Short & Long-Term Disability
- Legal Assistance
- Pet Insurance
- Critical Illness Insurance
- Accident Insurance
- Hospital Indemnity Insurance
- Commuter Benefits
- Well-Being Initiatives
- Peer-to-Peer Recognition
Company overview
GenScript ProBio is a global contract development and manufacturing organization (CDMO) specializing in advanced therapies, operating as a subsidiary of GenScript Biotech Corporation. Founded in 2020 and headquartered in Pennington, New Jersey, the company provides end-to-end CDMO services from drug discovery to commercialization, with a particular focus on cell and gene therapies, biologics, and recombinant protein drugs. ProBio's comprehensive service portfolio includes plasmid DNA manufacturing, viral vector production (AAV and lentiviral platforms), antibody discovery, mRNA vaccines, and antibody-drug conjugates. The company operates state-of-the-art GMP facilities, including a flagship 128,000 sq ft Cell and Gene Therapy Center of Excellence in Hopewell, New Jersey, which supports clinical-stage development and manufacturing. With expertise spanning CGT, antibody development, and protein therapeutics, ProBio aims to accelerate drug development timelines for biopharmaceutical innovators through proactive strategies, professional solutions, and efficient processes. The company has supported over 135 IND programs globally and employs advanced technologies to streamline therapeutic development from concept to clinic.