Research Assistant I - Dr. Ian Guldner
Salk Institute Office of Technology Development
Summary
As a Research Assistant I, this position will support the laboratory of Dr. Ian Guldner, which investigates how cells communicate with one another through the exchange of proteins and how these communication networks change during aging, neurodegeneration, and disease. The Guldner Lab combines cell-specific protein tagging, advanced cell isolation approaches, molecular and cellular biology, and in vivo and in vitro models to identify proteins exchanged between different cell types and understand how these interactions influence tissue function and disease. The laboratory also uses genetic and pharmacologic approaches to investigate whether modifying cellular communication networks can influence aging and neurodegenerative processes.
Job description
Under direct supervision, the Research Assistant I will support ongoing research projects by performing established laboratory procedures, maintaining biological samples and experimental materials, assisting with mouse-related research activities, collecting and documenting data, and supporting general laboratory operations. The position will receive training in laboratory-specific techniques and is expected to maintain accurate records, follow established protocols, and communicate experimental results to members of the research team.
What Your Key Responsibilities Will Be
- Perform routine molecular and cellular biology procedures in support of studies investigating intercellular protein communication, aging, and neurodegeneration.
- Support experiments involving biological samples and mouse models, including experimental procedures on live mice such as compound treatment, behavioral analyses, and tissue collection.
- Assist with molecular biology techniques such as DNA/RNA preparation, PCR, protein sample preparation, and other established assays as required by individual projects.
- Works on problems of moderate scope in which analysis of situation or data requires the review of identifiable factors.
- Exercises judgment within defined procedures and practices to determine appropriate action.
- Maintain accurate experimental records, organize research data, and assist with basic data analysis and presentation of findings to the research team.
- Maintain laboratory reagents, biological samples, freezer inventories, and shared supplies; assist with ordering and general laboratory organization.
- Follow institutional laboratory safety, biosafety, and animal research requirements and maintain a clean and organized work environment.
- Follow directions and abide by lab expectations.
- Flexibly performs other related duties as assigned by management.
What we Require
- No professional experience required.
- Education: Bachelor's degree in Biological Sciences or related scientific discipline required.
- A minimum of 2 years of experience in a scientific role is required for consideration of a Bachelor's degree in a different discipline.
- Computer skills required: Microsoft Office; R Studio; Accounting Software; Inventory Software; Human Resource Systems
Other skills (preferred)
- Prior experience or internships in a laboratory setting.
- Prior experience with molecular biology, cell biology, in vivo research, direct handling of and experimentation with mice, and mass spectrometry-based protein analysis.
- Basic knowledge of laboratory procedures and safety practices.
- Familiarity with basic molecular and cellular biology techniques, microscopy, and tissue dissociation and cell isolation.
- Interest in aging biology, neuroscience, neurodegeneration, proteomics, or cell-to-cell communication.
- Basic familiarity with laboratory safety and research compliance.
Requirements
- No professional experience required
- Bachelor's degree in Biological Sciences or related scientific discipline required
- A minimum of 2 years of experience in a scientific role is required for consideration of a Bachelor's degree in a different discipline
- Computer skills required: Microsoft Office; R Studio; Accounting Software; Inventory Software; Human Resource Systems
Benefits
- Medical, Dental & Vision
- Retirement
- Paid time off
- Tuition reimbursement
- Patient advocacy services
- Transit/parking program
Company overview
The Salk Institute Office of Technology Development (OTD) serves as the technology transfer and commercialization arm of the prestigious Salk Institute for Biological Studies. Aligned with Salk's vision "Where Cures Begin," OTD is dedicated to translating groundbreaking scientific discoveries into marketplace solutions that maximize positive impact on humanity. The office manages the intellectual property portfolio of the Institute, providing comprehensive support for intellectual property protection, licensing, business development, and technology transfer activities. OTD works closely with Salk's research community to evaluate promising technologies, develop commercialization strategies, and negotiate licensing agreements with pharmaceutical, biotechnology, and venture partners. The team implements creative deal structures to facilitate the translation of scientific innovations into practical applications, with expertise spanning aging, immunology, neuroscience, plant biology, and cancer research. By bridging the gap between academic research and industry application, OTD plays a crucial role in ensuring that Salk's scientific breakthroughs reach patients and society through commercial partnerships and startup ventures.