Research Associate I – Imaging
Allen Institute
Summary
We are looking for a Research Associate I as part of an interdisciplinary team working on spatial transcriptomics. The goal of our team is to produce high quality in situ hybridization data in order to characterize cell types in the brain. This person is responsible for executing a variety of laboratory tasks and/or experiments in a high-throughput laboratory environment following Standard Operating Procedures (SOPs). Good judgment and problem-solving skills are required for process development, recognizing process deviations, participating in troubleshooting, and operation of complex laboratory instrumentation.
Job description
Essential Functions
- Operate fluorescence imaging microscopes
- Handling of mouse and human tissue
- Perform multiple histological staining processes (Nissl, IHC, Biocytin, ISH)
- Prepare and assemble custom slides and imaging chambers
- Operate MERSCOPE, Xenium and any other imaging equipment within the team
- Compile, process and analyze data; evaluate and communicate research results
- Evaluate, calibrate, and troubleshoot experiment quality and instrument functionality
- Contribute to a rigorously scientific, cohesive and efficient team environment
- Maintain accurate laboratory documentation using established methods, which may include Microsoft Office, Custom Laboratory Information Management System (LIMS), and other packages
- Follow Standard Operating Procedures, good laboratory practices, and comply with all regulatory requirements
- Other duties as assigned
Required Education And Experience
- Bachelor’s degree in a life science or related field
- Basic knowledge of neuroscience and cell biology
Preferred Education And Experience
- Exceptional manual dexterity and attention to detail
- Strong scientific communication skills (written and oral)
- 0-2 years experience working in a laboratory setting
- Laboratory experience with cell or molecular biology
- Hands-on experience working with microscopes
- Strong computer skills, knowledge of databases, and reading/running scripts
- Understanding of custom imaging software programs
Work Environment
Laboratory environment, including potential exposure to lasers, biohazards. Occasional exposure to safety hazards, noises, change in temperature, chemicals, and other hazardous materials and machinery. Exposure to Class IV lasers.
Physical Demands
- Stooping, bending, crouching
- Reaching, or climbing ladders
- Must be able to resolve red/green colors
- Fine motor movements in fingers/hands to operate computers and other office equipment, lab equipment
Position Type/Expected Hours of Work
This role is currently working onsite and is expected to work onsite for the majority of working hours. The primary work location for this role is 615 Westlake Ave N. Occasional weekend hours may be required.
Requirements
- Bachelor’s degree in a life science or related field
- Basic knowledge of neuroscience and cell biology
- Exceptional manual dexterity and attention to detail
- Strong scientific communication skills (written and oral)
- 0-2 years experience working in a laboratory setting
- Laboratory experience with cell or molecular biology
- Hands-on experience working with microscopes
- Strong computer skills, knowledge of databases, and reading/running scripts
- Understanding of custom imaging software programs
Benefits
- Medical Insurance
- Dental Insurance
- Vision Insurance
- Basic Life Insurance
- 401(k)
- Paid Time Off
- Relocation Assistance
Company overview
The Allen Institute is a premier non-profit research organization founded in 2003 by philanthropist Paul G. Allen, co-founder of Microsoft. Headquartered in Seattle, Washington, the institute is dedicated to answering fundamental questions in biology and accelerating scientific discovery through large-scale, collaborative research projects. The organization operates several major research divisions including the Allen Institute for Brain Science, Allen Institute for Cell Science, and Allen Institute for Immunology. The Allen Institute is renowned for creating comprehensive, open-access data resources and tools for the global scientific community, such as the Allen Brain Atlas, which provides detailed maps of gene expression in the mouse and human brain. Their research approach combines experimental biology with computational analysis and data science to generate transformative insights into complex biological systems. The institute's work has significantly advanced understanding of brain function, cellular biology, and immune system dynamics, making it a leading force in modern biomedical research with a strong commitment to open science and data sharing.