Research Associate I, Process Development
BlueRock Therapeutics
Summary
BlueRock Therapeutics is seeking a Research Associate I, Process Development in New York City, NYC. As a central development resource at the company, the Process Development team works closely with research, non-clinical, analytical, manufacturing, and quality teams. The successful candidate will be a key technical contributor to a dynamic and progressive team focused on development, scale up, and tech transfer the end-to-end manufacturing process for authentic and engineered cellular products. The ability to communicate complex topics and assume a broad range of responsibilities is critical. Hands-on experience with mammalian cell culture (ideally PSCs and differentiated cell products) is essential.
Job description
Responsibilities
- Participate in the execution of in vitro experiments to develop, optimize, and characterize scalable processes for phase appropriate manufacture of pluripotent stem cells, and differentiated cellular products working within your team
- Ability to follow provided standard operating procedures, batch records and other process documentation
- Perform process analytics to monitor the process performance, improve process understanding and characterize pluripotent stem cells and differentiated cellular products
- Conduct assigned routine tasks in the laboratory with minimal supervision
- Analyze and document experimental data in electronic laboratory notebooks in a timely and accurate manner in accordance with the company quality management system.
- Attend and participate in internal and external meetings as required.
Minimum Requirements
- Minimum of a Bachelors degree in a relevant field, including but not limited to: biological sciences, biomedical sciences, bioengineering, biochemistry, neurology
- Basic wet lab skills, including mammalian cell culture and basic aseptic technique is required
- Familiarity with cell characterization methods and technologies, such as flow cytometry, qPCR, immunoassays, and microscopy is required
- Understanding of, or experience with, bioreactor systems is desired
- Demonstrated ability to follow experimental plans and independently execute complex tasks
- Strong English written and verbal communications skills
- Able to work independently and as part of a team in a fast-paced environment.
- Excellent organizational skills are required.
Work Environment
- In this position you will work in a controlled laboratory environment
- On-site work after-hours and weekends is routinely required.
- You may be periodically required to move heavy equipment up to 50lbs
- There is a risk of potential exposure to chemicals and biohazards consistent with somatic cell therapy culture
- Working in the laboratory requires mandatory use of personal protective equipment
Requirements
- Minimum of a Bachelors degree in a relevant field, including but not limited to: biological sciences, biomedical sciences, bioengineering, biochemistry, neurology
- Basic wet lab skills, including mammalian cell culture and basic aseptic technique is required
- Familiarity with cell characterization methods and technologies, such as flow cytometry, qPCR, immunoassays, and microscopy is required
- Understanding of, or experience with, bioreactor systems is desired
- Demonstrated ability to follow experimental plans and independently execute complex tasks
- Strong English written and verbal communications skills
- Able to work independently and as part of a team in a fast-paced environment.
- Excellent organizational skills are required.
Company overview
BlueRock Therapeutics is a clinical-stage biotechnology company pioneering engineered cell therapies for the treatment of devastating neurological and ophthalmic diseases. Founded in 2016 as a joint venture between Versant Ventures and Leaps by Bayer, the company became a wholly owned, independently operated subsidiary of Bayer AG in late 2019. BlueRock leverages its proprietary induced pluripotent stem cell (iPSC) platform to develop novel cellular medicines that aim to transform disease treatment through regenerative approaches. The company's pipeline includes two clinical-stage programs: bemdaneprocel (BRT-DA01) for Parkinson's disease and OpCT-001 for primary photoreceptor diseases affecting vision. With operations spanning Cambridge, Massachusetts; Toronto, Ontario; New York; and Berlin, BlueRock employs 201-500 professionals dedicated to advancing cell and gene therapies. The company's mission centers on harnessing the power of cell therapy to create breakthrough medicines for patients with limited treatment options, operating at the intersection of neurology, cardiology, and immunology research.