Research Associate/Senior Research Associate, Cell Engineering
Colossal Biosciences
Summary
An affiliate of Colossal is looking for a talented research associate in cell biology with an interest in the derivation, characterization, and gene editing in non-model mammalian organisms. You will work closely with other lab team members in efforts to innovate on protocols of genome editing, reprogramming and lineage differentiation using cutting edge technologies.
Job description
This position is based on-site in Dallas, TX. Relocation assistance is available.
Duties and Responsibilities
- Derive and characterize stable cell lines from primary tissues
- Microdissection skills for cell line derivations
- Test novel cell culture conditions and delivery methods to optimize gene editing
- Expand clonal cell lines for cryopreservation, genotyping and QC assays
- Work with team members to interrogate targeting, genotyping and QC workflows
- Assist with making edited cell lines that meet quality control criteria for downstream SCNT
- Schedule, analyze and execute experiments to deliver on project milestones
- Attend lab meetings, prepares reports and presentations on the progress of projects
- Demonstrate great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities
- Experience in primary cell line derivation, culture optimization and cryopreservation
- Experience with electroporation and transfection to maximize gene delivery and viability
- Experience immunostaining cells for flow cytometry and fluorescent microscopy
- Exceptional aseptic technique as antibiotic free cultures are standard
- Organized and comfortable multi-tasking to deliver on concurrent projects on time
- Strong written and oral communication skills, as well as creative problem-solving skills
Preferred Skills and Abilities
- Experience with high throughput imaging platforms and data analysis
- Experience with automated cell culture systems
- Experience with stem cell culture, such as mouse embryonic stem cells (mESC) or induced pluripotent stem cells (iPSC)
Education and Experience
- BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field.
Requirements
- Experience in primary cell line derivation, culture optimization and cryopreservation
- Experience with electroporation and transfection to maximize gene delivery and viability
- Experience immunostaining cells for flow cytometry and fluorescent microscopy
- Exceptional aseptic technique as antibiotic free cultures are standard
- Organized and comfortable multi-tasking to deliver on concurrent projects on time
- Strong written and oral communication skills, as well as creative problem-solving skills
- BA/BS/MA/MS in biological sciences, bioengineering, molecular biology, genetics, or any science related field
Benefits
- Medical, Dental & Vision
- Paid Time Off
- Company Holidays
- Flexible Spending Accounts
- 401(k) Matching
- Paid Parental Leave
- Education Reimbursement
Company overview
Colossal Biosciences is a pioneering American biotechnology and genetic engineering company founded in 2021 by Harvard geneticist George Church and serial entrepreneur Ben Lamm. Headquartered in Dallas, Texas, the company specializes in developing radical new technologies to advance the field of genomics and species restoration. Colossal is the first company to apply CRISPR gene-editing technology for the purpose of species de-extinction, beginning with ambitious projects to revive the woolly mammoth, Tasmanian tiger, dodo bird, dire wolf, and other extinct species. The company's mission extends beyond de-extinction to include protection of critically endangered species and repopulation of critical ecosystems that support biodiversity and ecosystem health. With over 170 scientists and advisors, Colossal combines cutting-edge genetic engineering with conservation biology to address the global biodiversity crisis. The company has raised significant funding, achieving unicorn status and becoming Texas' first decacorn with a valuation exceeding $10 billion. Beyond its scientific endeavors, Colossal has spun out software platforms like Form Bio and established the Colossal Foundation to support conservation efforts worldwide.