Research Associate, Stem Cell Engineering
Colossal Biosciences
Summary
An affiliate of Colossal Biosciences is looking for a talented stem cell biologist with an interest in the manipulation of avian embryonic stem cells. You will work closely with other lab team members in efforts to innovate on protocols of avian stem cell culture, genome editing, and reintroduction into embryos using cutting edge technologies.
Job description
This position is based in Dallas, TX. Relocation assistance is available.
Duties and Responsibilities
- Culture avian embryonic stem cells, test novel cell culture conditions, transfect cells, sort monoclonal cell lines, screen and expand cells according to latest protocols and newly developed approaches
- Using a dissection microscope, collect avian blastodiscs from avian embryos and derive stem cell cultures
- Characterize and QC avian stem cell cultures
- Inject stem cells into avian blastodiscs
- Work with team members to assess efficiency of editing through NGS sequencing approaches
- Attends lab meetings, prepares reports, and presentations on the progress of projects
- Great organizational skills and excellent laboratory record maintenance
Required Skills and Abilities
- Experience with embryonic stem cell cultures
- Experience manipulating embryos under a microscope
- Experience in cell line derivation, culture, propagation, and transfection methodologies
- Experience in molecular biology (eg, nucleic acid and protein extraction, gel electrophoresis)
- Experience with flow cytometry, immunostaining, cell microscopy
- Strong written and oral communication skills, as well as creative problem-solving skills
Education and Experience
- BA/BS/MA/MS in biological sciences, cell biology, bioengineering, molecular biology, genetics, or any science related field.
Requirements
- Experience with embryonic stem cell cultures
- Experience manipulating embryos under a microscope
- Experience in cell line derivation, culture, propagation, and transfection methodologies
- Experience in molecular biology (eg, nucleic acid and protein extraction, gel electrophoresis)
- Experience with flow cytometry, immunostaining, cell microscopy
- Strong written and oral communication skills, as well as creative problem-solving skills
- BA/BS/MA/MS in biological sciences, cell biology, bioengineering, molecular biology, genetics, or any science related field
Benefits
- Medical, Dental & Vision
- Paid Time Off
- Company Holidays
- Flexible Spending Accounts
- 401(k) Matching
- Paid Parental Leave
- Education Reimbursement
- Relocation Assistance
Company overview
Colossal Biosciences is a pioneering American biotechnology and genetic engineering company founded in 2021 by Harvard geneticist George Church and serial entrepreneur Ben Lamm. Headquartered in Dallas, Texas, the company specializes in developing radical new technologies to advance the field of genomics and species restoration. Colossal is the first company to apply CRISPR gene-editing technology for the purpose of species de-extinction, beginning with ambitious projects to revive the woolly mammoth, Tasmanian tiger, dodo bird, dire wolf, and other extinct species. The company's mission extends beyond de-extinction to include protection of critically endangered species and repopulation of critical ecosystems that support biodiversity and ecosystem health. With over 170 scientists and advisors, Colossal combines cutting-edge genetic engineering with conservation biology to address the global biodiversity crisis. The company has raised significant funding, achieving unicorn status and becoming Texas' first decacorn with a valuation exceeding $10 billion. Beyond its scientific endeavors, Colossal has spun out software platforms like Form Bio and established the Colossal Foundation to support conservation efforts worldwide.