Research Fellow

Job Summary

The Koo Laboratory in the Division of Infectious Diseases at Brigham and Women's Hospital, Harvard Medical School, is seeking highly motivated post-doctoral Research Fellow candidates. The lab is dedicated to the development and application of novel diagnostic approaches for infections in immunocompromised hosts and the delineation of the epidemiology and pathophysiology of opportunistic pathogens, especially fungi, in these patient populations.

The candidate will be expected to have experience, or a high capacity to learn, murine pneumonia models, and molecular genetic techniques including spatial transcriptomic studies, and microbiologic/mycologic laboratory techniques. The team includes the Principal Investigator and other collaborating faculty, research scientists, postdoctoral fellows, and research assistants.

Principal Duties and Responsibilities

• Design, execute, and interpret research experiments
• Learn molecular genomics techniques including single-cell RNAseq (scRNAseq), spatial transcriptomics, and other methods
• Maintain murine models and process murine tissues for more detailed evaluation
• Use advanced analytical chemistry techniques to define the breath volatile metabolite profile of patients with various bacterial, viral, and fungal pneumonias
• Analyze mass spectroscopic and differential mobility spectroscopic data from laboratory experiments
• Maintain a detailed record of experiments in a laboratory notebook
• Independently follow detailed protocols while working closely with a wide range of lab members
• Assist in training new Research Assistants and Postdoctoral Fellows
• Troubleshoot problems and instruct others in highly specialized techniques
• Investigate, create, and develop new methods and technologies for research advancements
• Prepare written data reports, including methodology, figure preparations, and manuscript/progress report descriptions
• Contribute to research presentations at local, national, and international meetings
• Oversee laboratory research assistants and students, including training and assisting with experimental design and implementation
• Organize and/or draft material for research papers, manuscripts, or other documents for publication and/or presentation

Qualifications

• MD or PhD in a relevant biological field (received or expected soon)
• Excellent English verbal and written communication skills
• Able to work both independently and in a team
• Interest in learning and troubleshooting new molecular biology techniques
• Familiarity with animal modeling of disease
• Excellent organizational and communication skills
• Excellent interpersonal skills and ability to supervise and train staff effectively
• Ability to prioritize tasks, set deadlines, and adapt to shifting priorities

Education and Experience

• Minimum Required: Doctoral Degree
• Preferred: Doctoral Degree
• Required: Recent MD or PhD graduate, 1+ years of experience in a research-related field

Working Conditions

Work will be performed in the Thorn Research Building on the Brigham and Women's Hospital main campus, in Boston, MA.